4'-CHLORODIAZEPAM
4'-CHLORODIAZEPAM Basic information
- Product Name:
- 4'-CHLORODIAZEPAM
- Synonyms:
-
- 7-Chloro-1,3-dihydro-1-methyl-5-(4-chlorophenyl)-2H-1,4-benzodiazepin-2-one
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-
- Aids080743
- Aids-080743
- 7-chloro-1,3-dihydro-1-methyl-5-(p-chlorophenyl)-2h-1,4-benzodiazepin-2-one
- 7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2h-4-benzodiazepin-2-one
- 7-chloro-5-(p-chlorophenyl)-1,3-dihydro-1-methyl-2h-4-benzodiazepin-2-one
- chlorodiazepam
- CAS:
- 14439-61-3
- MF:
- C16H12Cl2N2O
- MW:
- 319.19
- Mol File:
- 14439-61-3.mol
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4'-CHLORODIAZEPAM Chemical Properties
- Melting point:
- 160-163 °C
- Boiling point:
- 517.1±50.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- +2C to +8C
- solubility
- ethanol: 17 mg/mL
- form
- Off-white powder
- pka
- 3.08±0.10(Predicted)
- BRN
- 685202
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 22-24/25
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- DF0500000
- F
- 10
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Hazardous Substances Data
- 14439-61-3(Hazardous Substances Data)
MSDS
- Language:English Provider:SigmaAldrich
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4'-CHLORODIAZEPAM Usage And Synthesis
Uses
4′-Chlorodiazepam has been used as a translocator protein ligand in mitochondrial functional studies. It has also been used to investigate its protective effects on glucose deprived T98G astrocyte cell lines.
Biochem/physiol Actions
4′-Chlorodiazepam (Ro5-4864) is a potent selective ligand for the mitochondrial translocator protein 18kDa (TSPO), formerly known as the peripheral benzodiazepine receptor (PBR). Ro5-4864 does not bind to GABA(A) receptors and lacks typical benzodiazepine effects, but has been found to be neuroprotective in several studies.
4'-CHLORODIAZEPAMSupplier
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel
- 025-66099280 17798518460
- cfzhang@aikonchem.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Shanghai Chaolan Chemical Technology Center
- Tel
- QQ:65489617 15618227136
- info@SuperLan-chem.com
Shanghai Pingguo Pharmaceutical Co., Ltd.
- Tel
- 021-20432229
- 2412110556@qq.com
Beijing OKA biological technology co., LTD
- Tel
- 010-010-62971590 18548936886
- 3462612863@qq.com
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4'-CHLORODIAZEPAM(14439-61-3)Related Product Information
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- N-ME-GLY-NME2
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- Benzophenone imine
- 4'-CHLORODIAZEPAM
- CHEMBRDG-BB 5668895
- 1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE
- MEDAZEPAM
- 4-CHLORO-O-TOLUIDINE HYDROCHLORIDE
- 4-CHLORO-N,N-DIMETHYLANILINE
- 1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one
- 4-CHLORO-2-METHYLACETANILIDE
- 4-CHLORO-N-METHYLFORMANILIDE