Benzophenone imine Chemical Properties

Melting point:

-30 °C

Boiling point:

151-153 °C10 mm Hg(lit.)

Density 

1.08 g/mL at 25 °C(lit.)

vapor pressure 

0.082Pa at 20℃

refractive index 

n20/D 1.618(lit.)

Flash point:

145 °C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMSO (Slightly), Ethyl Acetate (Slightly)

form 

Liquid

pka

pK1:6.82 (25°C)

color 

Clear colorless to light yellow-brownish

Water Solubility 

0.3 g/L (25 ºC)

BRN 

1100371

InChIKey

SXZIXHOMFPUIRK-UHFFFAOYSA-N

CAS DataBase Reference

1013-88-3(CAS DataBase Reference)

NIST Chemistry Reference

Benzenemethanimine, «alpha»-phenyl-(1013-88-3)

Safety Information

Hazard Codes 

Xi,N,Xn

Risk Statements 

36/37/38-51/53-38-22

Safety Statements 

26-36-61-37

RIDADR 

UN3082

WGK Germany 

3

HS Code 

29252900

MSDS

• Language:English Provider:Benzophenone imine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Benzophenone imine Usage And Synthesis

Chemical Properties

clear colorless to light yellow-brownish liquid

Uses

Useful in the preparation of nitrile ylide dimers.Benzophenone imine as ammonia surrogate. As intermediate material for synthesis of organic chemicals. Catalytic enantioselective alkylation of the benzophenone imine of glycine t-butyl ester using phosphazene (Schwesinger) bases and chiral quaternary ammonium salts yields either enantiomer of amino acid derivatives in excellent yield.

Uses

Benzophenone imine is useful in the preparation of nitrile ylide dimers.

Application

Benzophenone imine is a multifunctional reagent in organic synthesis, its core role being as an ammonia equivalent and a protecting group for primary amines. It reacts with primary amines to form stable Schiff bases, thereby protecting the functional groups of primary amines and preventing them from undergoing side reactions in subsequent reactions.

Synthesis Reference(s)

Synthetic Communications, 18, p. 1501, 1988 DOI: 10.1080/00397918808081307

Flammability and Explosibility

Not classified

Benzophenone imine(1013-88-3)Related Product Information

• 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
• Benzophenone
• 2,2',4,4'-Tetrahydroxybenzophenone
• 4-Chlorobenzophenone
• Benzophenone oxime
• Oxybenzone
• O-Phthalimide
• Imipenem
• Benzophenone hydrazone
• Ethyl N-(diphenylmethylene)glycinate
• diphenylmethanimine hydrochloride
• DIETHYL(DIPHENYLMETHYL) PHOSPHATE
• Dibenzoylmethane
• 9-FLUORENONE OXIME
• AURAMINE O
• Fluproquazone
• 2-AMINO-5-CHLOROBENZOPHENONE OXIME
• Ethyleneimine