Basic information Description Reference Safety Supplier Related

2-AMINO-5-CHLOROBENZOPHENONE OXIME

Basic information Description Reference Safety Supplier Related

2-AMINO-5-CHLOROBENZOPHENONE OXIME Basic information

Product Name:
2-AMINO-5-CHLOROBENZOPHENONE OXIME
Synonyms:
  • 2-AMINO-5-CHLOROBENZOPHENEONE OXIME
  • 2-AMINO-5-CHLOROBENZOPHENONE OXIME
  • AKOS 90376
  • TIMTEC-BB SBB003174
  • (2-amino-5-chlorophenyl)phenyl-methanonoxime
  • 2-amino-5-chlorobenzophenoneoxime,mixtureofsynandantiisomers
  • 2-Amino-5-chlorobenzophenoneα-oxime-,(Z)-
  • Mixtureofsyn-andanti-isomeres
CAS:
18097-52-4
MF:
C13H11ClN2O
MW:
246.69
EINECS:
241-999-5
Product Categories:
  • Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
Mol File:
18097-52-4.mol
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2-AMINO-5-CHLOROBENZOPHENONE OXIME Chemical Properties

Melting point:
117-120oC
Boiling point:
434.9±45.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
10.20±0.28(Predicted)
color 
Pale Yellow to Light Yellow
EPA Substance Registry System
Methanone, (2-amino-5-chlorophenyl)phenyl-, oxime (18097-52-4)
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Safety Information

Safety Statements 
24/25
HS Code 
29280090

MSDS

  • Language:English Provider:ACROS
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2-AMINO-5-CHLOROBENZOPHENONE OXIME Usage And Synthesis

Description

2-Amino-5-Chlorobenzophenone is in the form of a yellow-brown crystalline powder. Its melting point is 98-100°C. It is used to produce intermediates for the synthesis of Oxazolam drug and intermediates for psychotherapeutic agents, such as chlorodiazepoxide and diazepam.1,2

Reference

  1. R. Liao, Synthetic method of Oxazolam drug intermediate 2-amino-5-chlorobenzophenone, Patent CN105461576A
  2. S. Nakanishi, W. E. Barth, Process for preparing 6-chloromethyl-4-phenylquinazoline-3-oxide and intermediates therefor, Patent US3932325A

Chemical Properties

yellow crystalline powder

Uses

Intermediate in the preparation of Chlordiazepoxide (C327050) and its metabolites.

Definition

ChEBI: (2-amino-5-chlorophenyl)(phenyl)methanone oxime is a diarylmethane.

Synthesis Reference(s)

The Journal of Organic Chemistry, 30, p. 3957, 1965 DOI: 10.1021/jo01022a519

2-AMINO-5-CHLOROBENZOPHENONE OXIME Preparation Products And Raw materials

Preparation Products

7-chloro-1,3-dihydro-5-phenyl-2-oxo-2H-1,4-benzodiazepin-3-yl acetate6-CHLORO-2-(CHLOROMETHYL)-3-OXIDO-4-PHENYL-QUINAZOLINEDemoxepamChlordiazepoxide

Raw materials

Hydroxylamine hydrochlorideWater2-Amino-5-chlorobenzophenoneIsoxazole

2-AMINO-5-CHLOROBENZOPHENONE OXIMESupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Email
info@chemlin.com.cn
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Email
cdhxsj@163.com
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2-AMINO-5-CHLOROBENZOPHENONE OXIME(18097-52-4)Related Product Information