1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE Basic information
- Product Name:
- 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
- Synonyms:
-
- 5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one
- HYDROXYFASUDIL;HA-1100;HA 1100;HA1100
- 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
- 1H-1,4-Diazepine, hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-
- Ha 1100
- Hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1H-1,4-diazepine
- 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepinehydrochloride
- 5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol
- CAS:
- 105628-72-6
- MF:
- C14H17N3O3S
- MW:
- 307.37
- Product Categories:
-
- Angiogenesis and Metastasis
- Intracellular signaling
- Mol File:
- 105628-72-6.mol
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1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE Chemical Properties
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
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1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE Usage And Synthesis
Biological Activity
Cell-permeable active metabolite of Fasudil (HA 1077; Fasudil hydrochloride). Produces ATP-competitive and reversible inhibition of Rho-kinase and is ~ 100-fold selective over a range of other protein kinases. Inhibits neutrophil migration and produces potent vasodilatory effects in vivo .
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINESupplier
Suzhou Ran enzyme Biotechnology Co., Ltd. Gold
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- 0512-0512-62793604 18015430729
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3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Chembest Research Laboratories Limited
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- +86-21-20908456
- sales@BioChemBest.com
VDM Biochemicals
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- 0330-2528181
- sales@vdmbio.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
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1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE(105628-72-6)Related Product Information
- 5-Quinolinesulfonic acid, 2-methyl-
- Fasudil Impurity 6
- Fasudil Impurity 13
- Fasudil Pyridine N-Oxide TFA Salt
- Fasudil Impurity 9
- Fasudil Impurity 34
- Fasudil iMpurity
- Fasudil Impurity 7
- 1-[(1-Chloro-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine
- Fasudil Impurity 8
- 1-Chloro-5-isoquinolinesulfonic Acid
- Fasudil Impurity 6
- 1,4-ditosyl-1,4-diazepane
- Fasudil diMer
- Fasudil N-hydroxy iMpurity
- N-(3-HYDROXYPROPYL)ETHYLENEDIAMINE
- Isoquinoline
- HYDROXYFASUDIL MONOHYDROCHLORIDE