DEVAZEPIDE Chemical Properties

Boiling point:

758.6±60.0 °C(Predicted)

Density 

1.31±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: >5mg/mL

pka

13.25±0.40(Predicted)

form 

powder

color 

white to off-white

Safety Information

Hazard Codes 

T+

Risk Statements 

28

Safety Statements 

28-36/37-45

RIDADR 

UN 2811 6.1 / PGI

WGK Germany 

3

RTECS 

NL5994460

DEVAZEPIDE Usage And Synthesis

Uses

Antagonist (cholecystokinin).

Uses

Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.

General Description

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.

Biochem/physiol Actions

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.

storage

Store at +4°C

DEVAZEPIDE(103420-77-5)Related Product Information

• Pranazepide
• N-(2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-ACETAMIDE
• 3-AMINO-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
• DEVAZEPIDE
• tarazepide
• 3-AMINO-5-METHYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE