DEVAZEPIDE

Product Name: DEVAZEPIDE
CAS No.: 103420-77-5
Chemical Name: DEVAZEPIDE
Synonyms: 718;MK-329;L-364718;evazepide;DEVAZEPIDE;EVAZEPIDE, PANOS;Betaxolol Impurity 12;(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one;(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide;N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
CBNumber: CB7849798
Molecular Formula: C25H20N4O2
Formula Weight: 408.45
MOL File: 103420-77-5.mol

More

Less

DEVAZEPIDE Property

Boiling point:: 758.6±60.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >5mg/mL
form: powder
pka: 13.25±0.40(Predicted)
color: white to off-white
InChI: 1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)/t23-/m1/s1
InChIKey: NFHRQQKPEBFUJK-HSZRJFAPSA-N
SMILES: CN1C(=O)[C@@H](NC(=O)c2cc3ccccc3[nH]2)N=C(c4ccccc4)c5ccccc15

More

Less

Safety

Hazard Codes: T+
Risk Statements: 28
Safety Statements: 28-36/37-45
RIDADR: UN 2811 6.1 / PGI
WGK Germany: 3
RTECS: NL5994460
Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications: Acute Tox. 1 Oral

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3821
Product name: Devazepide
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $227
Updated: 2026/03/19

Sigma-Aldrich

Product number: D3821
Product name: Devazepide
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $909
Updated: 2026/03/19

Tocris

Product number: 2304
Product name: Devazepide
Purity: ≥99%(HPLC)
Packaging: 10
Price: $270
Updated: 2021/12/16

Tocris

Product number: 2304
Product name: Devazepide
Purity: ≥99%(HPLC)
Packaging: 50
Price: $1135
Updated: 2021/12/16

TRC

Product number: D535518
Product name: Devazepide
Packaging: 5mg
Price: $195
Updated: 2021/12/16

More

Less

DEVAZEPIDE Chemical Properties,Usage,Production

Uses

Antagonist (cholecystokinin).

Uses

Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.

General Description

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.

Biochem/physiol Actions

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.

storage

Store at +4°C

DEVAZEPIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DEVAZEPIDE Suppliers

China 24 Germany 1 United Kingdom 4 United States 11 Global 40

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: doncunbiosci@gmail.com
Country: China
ProdList: 591
Advantage: 58

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: +86-0519-85788828 +86-13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 4032
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44896
Advantage: 58

Shanghai Dexuan Pharmaceutical Technology Co., Ltd

Tel: 1701086315
Fax: 1701086315@qq.com
Email: dexuanpharma@126.com
Country: China
ProdList: 9475
Advantage: 58

103420-77-5, DEVAZEPIDERelated Search:

Pranazepide N-(2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-ACETAMIDE 3-AMINO-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE DEVAZEPIDE tarazepide 3-AMINO-5-METHYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE

N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE

DEVAZEPIDE

EVAZEPIDE, PANOS

(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one

L-364718

MK-329

(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide

1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-

718

evazepide

Betaxolol Impurity 12

103420-77-5

C25H20N4O2