1-METHYL-BIO
1-METHYL-BIO Basic information
- Product Name:
- 1-METHYL-BIO
- Synonyms:
-
- MEBIO
- GSK-3 INHIBITOR XIV, CONTROL
- 1-METHYL-BIO
- (2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime
- Me6BIO
- 2H-Indol-2-one, 6-bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-1-methyl-, (3Z)-
- Glycogen synthase kinase-3,CDK,GSK-3,Aryl Hydrocarbon Receptor (AhR),Glycogen synthase kinase 3,Inhibitor,inhibit,AhR,Agonist,Cyclin dependent kinase,Aryl Hydrocarbon Receptor,MeBIO
- (2Z,3E)-6'-Bromo-3-(hydroxyimino)-1'-methyl-[2,3'-biindolinylidene]-2'-one
- CAS:
- 667463-95-8
- MF:
- C17H12BrN3O2
- MW:
- 370.2
- Mol File:
- 667463-95-8.mol
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1-METHYL-BIO Chemical Properties
- storage temp.
- Store at +4°C
- solubility
- Soluble to 10 mM in DMSO
- form
- Powder
- color
- Brown to reddish brown
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1-METHYL-BIO Usage And Synthesis
Uses
MeBIO is an indirubin, which has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases.
IC 50
GSK-3: 44 μM (IC50); Cdk1/cyclin B: 55 μM (IC50); Cdk5/p25: >100 μM (IC50)
storage
Store at +4°C
1-METHYL-BIOSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com