Basic information Safety Supplier Related

2'-hydroxy-5'-methoxypropiophenone

Basic information Safety Supplier Related

2'-hydroxy-5'-methoxypropiophenone Basic information

Product Name:
2'-hydroxy-5'-methoxypropiophenone
Synonyms:
  • 2'-hydroxy-5'-methoxypropiophenone
  • 1-(2-Hydroxy-5-methoxyphenyl)-1-propanone
  • Methoxamine Impurity 18
  • Methoxamine Impurity 7 HCl
  • Methoxamine ImpurityCl
CAS:
49710-99-8
MF:
C10H12O3
MW:
180.20048
EINECS:
2564400
Mol File:
49710-99-8.mol
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2'-hydroxy-5'-methoxypropiophenone Chemical Properties

Melting point:
47–49°C
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow
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2'-hydroxy-5'-methoxypropiophenone Usage And Synthesis

Uses

1-(2-Hydroxy-5-methoxyphenyl)-1-propanone can be used as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators.

Preparation

Preparation by Fries rearrangement of p-methoxyphenyl propionate,
with titanium tetrachloride without solvent at 120° for 1 h (74%)
with aluminium chloride in nitrobenzene at 80–100° for 2 h (41%).

2'-hydroxy-5'-methoxypropiophenoneSupplier

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