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(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide

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(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Basic information

Product Name:
(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide
Synonyms:
  • 1-(4-AcetaMido-2-acetylphenoxy)-2-hydroxy-3-isopropylaMinopropane
  • DL-3'-Acetyl-4'-[2-hydroxy-3-(isopropylaMino)propoxy]acetanilide
  • Acebutolol EP IMpurity B
  • Acebutolol Impurity B HCl
  • rac Diacetolol
  • N-{3-Acetyl-4-{(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy}phenyl}acetamide
  • Acebutolol Impurity 2 Monomer
  • Acebutolol EP Impurity B HCl
CAS:
22568-64-5
MF:
C16H24N2O4
MW:
308.37
EINECS:
245-088-3
Product Categories:
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
22568-64-5.mol
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(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Chemical Properties

Melting point:
128 - 131°C
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Light Yellow
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Safety Information

HS Code 
2933599550
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(±)-N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Usage And Synthesis

Uses

The principal metabolite of Acebutolol (A123800) with less β-adrenoceptor blocking potency but greater cardioselectivity (atrial relative to tracheal tissue. Acebutolol EP Impurity B.

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