Basic information Description References Safety Supplier Related
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Zinc acetate

Basic information Description References Safety Supplier Related

Zinc acetate Basic information

Product Name:
Zinc acetate
Synonyms:
  • Acetic acid, zinc(II) salt
  • aceticacid,zinc(ii)salt
  • ai3-04465
  • Dicarbomethoxyzinc
  • Zinc acetate, pure, 99%
  • zinc acetate solution
  • Zinkdi(acetat)
  • zinc(+2) cation diacetate
CAS:
557-34-6
MF:
C4H6O4Zn
MW:
183.48
EINECS:
209-170-2
Product Categories:
  • intermediates
  • Agrochemical Intermediates
  • Organic-metal salt
  • Catalysis and Inorganic Chemistry
  • Chemical Synthesis
  • Zinc
  • pharmaceutical raw material
  • Food Additives
Mol File:
557-34-6.mol
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Zinc acetate Chemical Properties

Melting point:
83-86 °C
Boiling point:
908°C
Density 
1.84 g/mL at 25 °C (lit.)
Flash point:
12 °C
storage temp. 
Inert atmosphere,Room Temperature
form 
Powder
color 
Yellow to brown to gray-green
Specific Gravity
1.84
Water Solubility 
Soluble in water, alcohol, dilute mineral acids and alkalies.
Sensitive 
Hygroscopic
Merck 
14,10128
InChIKey
DJWUNCQRNNEAKC-UHFFFAOYSA-L
CAS DataBase Reference
557-34-6(CAS DataBase Reference)
NIST Chemistry Reference
Zinc acetate(557-34-6)
EPA Substance Registry System
Zinc acetate (557-34-6)
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Safety Information

Hazard Codes 
Xn,N,Xi,F
Risk Statements 
36-50/53-22-11
Safety Statements 
26-60-61-39-16-7
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
AK1500000
TSCA 
Yes
HazardClass 
9
HS Code 
29152990
Hazardous Substances Data
557-34-6(Hazardous Substances Data)

MSDS

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Zinc acetate Usage And Synthesis

Description

Zinc acetate (chemical formula: Zn(O2CCH3)2) is a kind of salt commonly existing in the dihydrate form. It appears as colorless solid. It is produced through the reaction between zinc oxide with acetate acid. Given that zinc is an essential element for growth and development of human body, zinc acetate can be used as a dietary supplement for the treatment of zinc deficiency. It plays an important role for the synthesis of cholesterol, protein, and fats. It can also be used as an astringent, styptic and emetic. In industry, it has various kinds of applications including wood preservation, manufacturing of other zinc salts as well as ethylene acetate, being used as a dye mordant, and analytical reagent.

References

https://en.wikipedia.org/wiki/Zinc_acetate
https://pubchem.ncbi.nlm.nih.gov/compound/Zinc_acetate_dihydrate#section=GHS-Classification

Description

Zinc acetate is the chemical compound with the formula Zn(O2CCH3)2, which commonly occurs as a dihydrate Zn(O2CCH3)2(H2O)2. Both the hydrate and the anhydrous forms are colorless solids that are commonly used in chemical synthesis and as dietary supplements. Zinc acetates are prepared by the action of acetic acid on zinc carbonate or zinc metal. When used as a food additive, it has the E number E650.

Chemical Properties

White crystalline powder

Chemical Properties

Zinc acetate occurs as white crystalline, lustrous plates with a faint acetic odor and an astringent taste.

Physical properties

The acetate group is capable of binding to metal ions in a variety of ways through its two oxygen atoms and several connectivities are observed for the various hydrates of zinc acetate. Anhydrous zinc acetate adopts a polymeric structure consisting of zinc coordinated to four oxygen atoms in a tetrahedral environment, each tetrahedron being connected to neighbors by the acetate groups . The acetate ligands are not bidentate. In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.
2 - 5 - Heating pad
Heating Zn(CH3CO2)2 in a vacuum results in loss of acetic anhydride, leaving a residue of ""basic zinc acetate,"" with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be4O(OAc)6.

Uses

Zinc acetate is produced from acetic acid and zinc oxide. It is used for preserving wood, manufacturing glazers for painting on porcelain; as a reagent in testing for albumin, tannin, phosphate; as cross-linking agents for polymers; in tobacco smoke filters; and as a topical fungicide. Zinc acetate is an indirect food additive for use only as a component of adhesives.

Uses

Medicine (astringent), preserving wood, textile dyeing (mordant and resist), zinc chromate, laboratory reagent, cross-linking agent for polymers, ingredient of dietary supplements (up to 1 mg daily), feed additive, ceramic glazes.

Uses

Zinc acetate anhydrous is used in the synthesis of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis. It is utilized in the ultrasonic preparation of zinc sulfide nanoparticles coated on silica particles. It is administered orally or parenterally as a nutritional supplement. It finds an application in the field of industries such as wood preservation, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. It also acts as a plating inhibitor on primary water piping.

Production Methods

Zinc acetate is synthesized by reacting zinc oxide with glacial acetic acid, with subsequent crystallization, separation by centrifugation, and drying and milling of the crystals. No organic solvents are used during the synthesis.

Definition

ChEBI: An acetate salt in which the cationic component is zinc(2+).

Preparation

Zinc acetate is prepared by the reaction of acetic acid with zinc oxide followed by crystallization (crystals of dihydrate obtained): ZnO + 2CH3COOH → (CH3COO)2Zn + H2O.

Application

3–1-Dietary and medicinal applications
Zinc acetate is used as a dietary supplement and in lozenges used to treat the common cold. Zinc acetate alone is thought to be a more effective treatment than zinc gluconate. Zinc acetate can also be used to treat zinc deficiencies. As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for Wilson's disease. Zinc acetate is also sold as an astringent in the form of an ointment, a topical lotion; or combined with an antibiotic such as erythromycin for the topical treatment of acne. Furthermore Zinc acetate is commonly sold as a topical anti-itch ointment.
3–2-Industrial applications
Industrial applications include wood preserving, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. Zinc acetate is a precursor via a sol-gel route to the transparent semi conductor zinc oxide.

Pharmaceutical Applications

Zinc acetate has been used as an excipient in a variety of pharmaceutical formulations including topical gels, lotions, and solutions, and subcutaneous injections. It has also been investigated for use in an oral controlled-release formulation for water-soluble drugs in combination with sodium alginate and xanthan gum.
Therapeutically, zinc acetate has been used in oral capsules for the treatment of Wilson’s disease. Zinc acetate has also been demonstrated to be effective as a spermicide in vaginal contraceptives.

Safety

Zinc acetate is used in topical pharmaceutical formulations and subcutaneous injections, where it is generally regarded as relatively nontoxic and nonirritant when used as an excipient. However, zinc acetate is poisonous by intravenous and intraperitoneal routes; it is also moderately toxic following oral consumption.
Zinc acetate:
LD50 (rat, oral): 2.510 g/kg
LD50 (mouse, IP): 0.057 g/kg

Veterinary Drugs and Treatments

Zinc sulfate is used systemically as a nutritional supplement in a variety of species. Oral zinc acetate has been shown to reduce copper toxicity in susceptible dog breeds (Bedlington Terriers, West Highland White Terriers) with hepatic copper toxicosis. Zinc therapy may also be of benefit in the treatment of hepatic fibrosis in the dog. Zinc sulfate is used topically as an astringent and as a weak antiseptic both for dermatologic and ophthalmic conditions.

storage

Zinc acetate loses water of hydration above 101℃. Zinc acetate should be stored in an airtight container in a cool, dry, place.

Incompatibilities

Zinc acetate is incompatible with oxidizing agents, zinc salts, alkalis and their carbonates, oxalates, phosphates, and sulfides.

Regulatory Status

Included in the FDA Inactive Ingredients Database (SC injections; topical lotions and solutions). Included in medicines licensed in the UK.

Zinc acetate Preparation Products And Raw materials

Raw materials

Zinc acetateSupplier

Aikon International Limited Gold
Tel
025-58859352
Email
cfding@aikonchem.com
Products Intro
Product Name:Zinc acetate
CAS:557-34-6
Purity:95% HPLC或者GC Package:10G,5G;1G
Wuhan yuqing jiaheng pharmaceutical co. LTD
Tel
027-83855381
Email
xiaozhan0503@163.com
Products Intro
Product Name:Zinc acetate
CAS:557-34-6
Purity:99% Package:1kg;25kg;1吨
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro
Product Name:Zinc acetate, 99.99%
CAS:557-34-6
Purity:99.99% Package:100G;25G
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
+86-021-61259100
Email
int02@meryer.com
Products Intro
Product Name:Zinc acetate
CAS:557-34-6
Purity:99% Package:5g;25g Remarks:D68003
Alfa Aesar
Tel
400-610-6006; 021-67582000
Email
saleschina@alfa-asia.com
Products Intro
Product Name:Zinc acetate, anhydrous, 99.9+%
CAS:557-34-6
Package:10g Remarks:H33734