2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Basic information
- Product Name:
- 2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
- Synonyms:
-
- [S,(+)]-3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol
- 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(2-hydroxy-4-methoxyphenyl)-, (3S)-
- CAS:
- 20879-05-4
- MF:
- C16H16O4
- MW:
- 272.3
- Mol File:
- 20879-05-4.mol
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2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Chemical Properties
- Melting point:
- 156 °C
- Boiling point:
- 418.5±45.0 °C(Predicted)
- Density
- 1.282±0.06 g/cm3(Predicted)
- storage temp.
- -10 to -25°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 9.53±0.40(Predicted)
- form
- powder
- color
- white to beige
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2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Usage And Synthesis
Definition
ChEBI: The S-enantiomer of vestitol.
Biological Activity
Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities.
(+)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolis, licorice root and other sources th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml).