Torbafylline Chemical Properties

Boiling point:

534.7±60.0 °C(Predicted)

Density 

1.25±0.1 g/cm3(Predicted)

pka

15.28±0.29(Predicted)

Torbafylline Usage And Synthesis

Uses

Torbafylline is a PDE inhibitor. Torbafylline mitigates protein breakdown in rat skeletal muscle following burns by activating the PDE4/cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline suppresses the increased ubiquitin-proteasome-dependent protein degradation observed in the skeletal muscles of rats susceptible to cancer and sepsis[1].

References

[1] Okyayuz-Baklouti I. The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle. Eur J Pharmacol. 1989 Jul 4;166(1):75-86. DOI:10.1016/0014-2999(89)90685-7

Torbafylline(105102-21-4)Related Product Information

• 1-N-HEXYLTHEOBROMINE
• HYDROXY PENTOXIFYLLINE
• 1-N-BUTYL-3,7-DIMETHYLXANTHINE
• 1-(5-hydroxyhexyl)-3,7-dimethyl-purine-2,6-dione
• 1-N-PROPYL-3,7-DIMETHYLXANTHINE
• 1-(5-hydroxy-5-methylhexyl)-3-methylxanthine
• Torbafylline