ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Basic information
- Product Name:
- H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
- Synonyms:
-
- AMYLOID PRECURSOR PROTEIN BETA-SECRETASE INHIBITOR
- A4 PROTEIN PRECURSOR770 (662-675)
- BACE-IN-1
- LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-[STATINE]-VAL-ALA-GLU-PHE
- LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATINE)-VAL-ALA-GLU-PHE-OH
- LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATIN)-VAL-ALA-GLU-PHE-OH
- LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE
- KTEETSEVN(STAT)VAEF
- CAS:
- 350228-37-4
- MF:
- C73H118N16O27
- MW:
- 1651.81
- Product Categories:
-
- Pepetides
- peptides
- beta-SecretaseNeurobiology
- β-SecretaseEnzyme Inhibitors by Enzyme
- Amyloid beta-peptide and related
- peptide
- Alzheimers and Neurodegenerative Disease Research
- Neurodegenerative Disease Peptides
- Other Alzheimer Peptides
- OtherNeuropeptides
- Protease Inhibitor Specificity Index
- Protease Inhibitors
- R to
- Mol File:
- 350228-37-4.mol
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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Chemical Properties
- Boiling point:
- 1976.1±65.0 °C(Predicted)
- Density
- 1.317±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 3.48±0.10(Predicted)
- color
- white
- Sequence
- Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-{Sta}-Val-Ala-Glu-Phe
MSDS
- Language:English Provider:SigmaAldrich
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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Usage And Synthesis
Uses
β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase)[1].
References
[1] Lin Liu, et al. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide. Sensors and Actuators B: Chemical. Volume 266, 1 August 2018, Pages 246-254.
[2] Zhou Y, et al. Tyrosine-Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal-Organic Framework Composites as Electrochemical Tags. Chemistry. 2023 May 16;29(28):e202300450. DOI:10.1002/chem.202300450
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OHSupplier
Alabiochem Tech.Co., Ltd.
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- 512-58900862 400-0707518
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GL Biochem (Shanghai) Ltd
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
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- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
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- 021-50135380
- shchemsky@sina.com
Creative Peptides
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- info@creative-peptides.com