Amanozine Chemical Properties

Melting point:

235-236°

Boiling point:

311.95°C (rough estimate)

Density 

1.2986 (rough estimate)

refractive index 

1.6900 (estimate)

pka

3.79±0.10(Predicted)

Amanozine Usage And Synthesis

Originator

Amanozine,Onbio Inc.

Definition

ChEBI: Amanozine is a diamino-1,3,5-triazine.

Manufacturing Process

21.3 g (0.1 mole) of 1-phenylbiguanide hydrochloride were dissolved in hot water and the solution was added to 5.3 g (0.05 mole) sodium carbonate by stirring. On cooling 15 g of the needle crystals have fallen. They were heated to reflux with 80 ml of dry formic acid. Then 40-50 ml formic acid was distilled off. The residue was with water diluted, cooled with ice and the conc. alkali was added. The precipitate fallen. It was filtered off and recrystallized from 40-50% ethanol. The pure product 4-amino-2-anilino-1,3,5-triazine had MP: 232°-233°C.
Monochlorohydrate of it crystallized as long colorless needles melted at 258°- 260°C.

Therapeutic Function

Diuretic

Purification Methods

It crystallises from dioxane or 50% aqueous EtOH. [Beilstein 26 III/IV 1195.]

Amanozine(537-17-7)Related Product Information

• Fluorescent brightener 71
• REACTIVE BLUE 2
• 6-(CHLOROMETHYL)-N-PHENYL-1,3,5-TRIAZINE-2,4-DIAMINE
• CIBACRON BRILLIANT YELLOW 3G-P
• 2-AMINO-4-ANILINO-1,3,5-TRIAZINE HYDROCHLORIDE
• Fluorescent Brightener 28
• Reactive Red 3
• REACTIVE RED 4
• REACTIVE BLUE 5
• L-Mimosine (leucenol)
• Disodium 4,4'-bis[(4-anilino-6-methoxy-1,3,5-triazin-2-yl)amino]stilbene-2,2'-disulphonate
• 2-AMINO-4-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYLAMINO]-1,3,5-TRIAZINE 98
• 2-AMINO-4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]AMINO-1,3,5-TRIAZINE
• 2-AMINO-4-(2-FLUOROPHENYLAMINO)-1,3,5-TRIAZINE
• 4-[4-CHLORO-6-(1,2,3,4-TETRAHYDROQUINOLIN-1-YL)-1,3,5-TRIAZIN-2-YL]MORPHOLINE
• 2-AMINO-4-(2,4-DIFLUOROPHENYLAMINO)-1,3,5-TRIAZINE
• 4-[4-CHLORO-6-(1,2,3,4-TETRAHYDROQUINOLIN-1-YL)-1,3,5-TRIAZIN-2-YL]-2,6-DIMETHYLMORPHOLINE
• BUTTPARK 18\01-78