2-Hexanamidoacetic acid Chemical Properties

Melting point:

90-92°C

Boiling point:

387.2±25.0 °C(Predicted)

Density 

1.074±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

3.60±0.10(Predicted)

color 

White to Off-White

2-Hexanamidoacetic acid Usage And Synthesis

Description

Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during cancer, while they are decreased 20-fold in mice following treatment with the PPARα ligand Wy 14643.

Chemical Properties

White Solid

Uses

An acylaminoacid derivative as antipsychotic drug.

Definition

ChEBI: An N-acylglycine in which the acyl group is specified as hexanoyl.

2-Hexanamidoacetic acid(24003-67-6)Related Product Information

• Sodium Cocoyl Glycinate
• Glycine ethyl ester hydrochloride