Basic information Safety Supplier Related

Colchicine, N-methyl-

Basic information Safety Supplier Related

Colchicine, N-methyl- Basic information

Product Name:
Colchicine, N-methyl-
Synonyms:
  • Colchicine, N-methyl-
  • N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-N-methylacetamide
  • N-Acetylcolchamine
  • N-Acetyldemecolcine
  • N-Methylcolchicine
  • Acetamide, N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
  • N-Acetaminophen
  • NSC 403155
CAS:
7336-40-5
MF:
C23H27NO6
MW:
413.46
Mol File:
7336-40-5.mol
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Colchicine, N-methyl- Usage And Synthesis

Description

A colchicine type alkaloid, N-acetyldemecolcine occurs in both the corms and seeds of Colchicum autumnale, Gloriosa virescens and Littoria modesta. It is separated from the numerous other accompanying bases by column and thin_x0002_layer chromatography. The base is laevorotatory with a specific rotation of [α]D - 2440 (c 1.0, CHC13).

Uses

Micromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC50 values of 10.93 and 12.38 μM[1].

References

Potesilova, Hrbek, Santavy, Collect. Czech. Chem. Commun., 32, 141 (1967)

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