Ono 1082
Ono 1082 Basic information
- Product Name:
- Ono 1082
- Synonyms:
-
- Ono 1082
- L-Leucine, N-[7-[(1R,2R,3R)-2-[(1E,3S)-3-[(1S,3S)-3-butylcyclopentyl]-3-hydroxy-1-propenyl]-3-hydroxy-5-oxocyclopentyl]-1,6-dioxoheptyl]- (9CI)
- CAS:
- 111111-04-7
- MF:
- C30H49NO7
- MW:
- 535.71
- Mol File:
- 111111-04-7.mol
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Ono 1082 Chemical Properties
- Boiling point:
- 752.2±60.0 °C(Predicted)
- Density
- 1.148±0.06 g/cm3(Predicted)
- pka
- 3.65±0.10(Predicted)
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Ono 1082 Usage And Synthesis
Description
Ono 1082 is a drug that increases cAMP levels in hepatocytes in rats.
Uses
ONO 1082 is a Prostaglandin E1 (PGE1) (HY-B0131) derivative and increases cAMP level in hepatocytes. ONO 1082 competes with the action of the cholestatic factor through the increase in the cAMP level[1].
References
[1] Kioka K, et al. [Effects of the cholestatic factor and the prostaglandin E1 derivative on the level of cAMP in isolated hepatocytes of rats]. Nihon Shokakibyo Gakkai Zasshi. 1989 Jan;86(1):45-9. Japanese. PMID:2543851