symphytine Chemical Properties

Boiling point:

508.85°C (rough estimate)

Density 

1.2168 (rough estimate)

refractive index 

1.5614 (estimate)

pka

12.59±0.29(Predicted)

IARC

3 (Vol. 31, Sup 7) 1987

Safety Information

RIDADR 

1544

HazardClass 

6.1(b)

PackingGroup 

III

symphytine Usage And Synthesis

Description

This pyrrolizidine alkaloid occurs in the roots of Symphytum officinale Linn. and is difficult to crystallize. The above structure has been proposed on the basis of chemical degradation and spectroscopic evidence.

Definition

ChEBI: A but-2-enoate ester obtained by formal condensation of the carboxy group of (2E)-2-methylbut-2-enoic acid with the 1-hydroxy group of (1R,7aR)-7-({[(2S,3S)-2,3-dihydroxy- -isopropylbutanoyl]oxy}methyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-ol.

References

Furuya, Araki., Chem. Pharm. Bull. (Tokyo), 16,2512 (1968)
Structure: Furuya, Hikichi., Phytochem., 10, 2217 (1971)

symphytine(22571-95-5)Related Product Information

• lasiocarpine
• 3-PROPOXYPYRROLIDINE
• SEC-BUTYL TIGLATE
• 2,3,5,7A-TETRAHYDRO-1H-PYRROLIZINE
• ALLYL 2-ETHYLBUTYRATE
• symphytine