lactoquinomycin B
lactoquinomycin B Basic information
- Product Name:
- lactoquinomycin B
- Synonyms:
-
- lactoquinomycin B
- 3a,11b-Dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-β-D-arabino-hexopyranosyl]-5a,11a-epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione
- 5a,11a-Epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione, 3a,11b-dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-β-D-arabino-hexopyranosyl]-
- CAS:
- 101342-94-3
- MF:
- C24H27NO9
- MW:
- 473.47
- Mol File:
- 101342-94-3.mol
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lactoquinomycin B Chemical Properties
- Melting point:
- 149-152 °C (decomp)
- Boiling point:
- 736.8±60.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- pka
- 6.15±0.40(Predicted)
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lactoquinomycin B Usage And Synthesis
Uses
Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively[1].
References
[1] T Okabe, et al. Lactoquinomycin B, a novel antibiotic. J Antibiot (Tokyo). 1986 Jan;39(1):1-5.
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lactoquinomycin B(101342-94-3)Related Product Information
- 6-OXO-6-(4-N-PENTYLPHENYL)HEXANOIC ACID
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone
- 6-BUTYL[1,2,3,4-TETRAHYDRONAPHTHALENE]
- 1-(4-Isobutylphenyl)ethanol
- 6-METHYL-1-TETRALONE
- lactoquinomycin B
- 5-Hydroxy-1-tetralone
- 7-(2,5-DIMETHYLPHENYL)-7-OXOHEPTANOIC ACID
- 3-(2-ethylbutoxy)propionic acid
- 2-(3-PHENYLPROPYL)TETRAHYDROFURAN
- 1A,7A-DIHYDRONAPHTHO[2,3-B]OXIRENE-2,7-DIONE
- 3-HYDROXY-2-METHYL-1-PHENYL-HEXAN-1-ONE
- 6-(4-HEXYLPHENYL)-6-OXOHEXANOIC ACID
- 6-(4-ETHYLPHENYL)-6-OXOHEXANOIC ACID
- 1-(4-HYDROXYMETHYL-PHENYL)-PENTAN-1-ONE