WIN 62005
WIN 62005 Basic information
- Product Name:
- WIN 62005
- Synonyms:
-
- WIN 62005
- 2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-5-methyl-6-(4-pyridinyl)-
- Win62005,Win 62005
- CAS:
- 152633-54-0
- MF:
- C12H10N4O
- MW:
- 226.23
- Mol File:
- 152633-54-0.mol
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WIN 62005 Chemical Properties
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 7.36±0.60(Predicted)
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WIN 62005 Usage And Synthesis
Uses
Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively.
in vivo
After p.o. administration of 1 mg/kg Win-62005, LVdP/dtmax is significantly increased in 30 min and remains increased for at least 6 h[1].
References
[1] Dundore RL, et al. Species-dependent pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 58993 and WIN 62005. J Cardiovasc Pharmacol. 1995 Jan;25(1):14-21. DOI:10.1097/00005344-199501000-00004
WIN 62005Supplier
MedChemexpress LLC
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- 021-58955995
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TargetMol Chemicals Inc.
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- +1-781-999-5354; +17819995354
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Beijing Jin Ming Biotechnology Co., Ltd.
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- 010-60605840 15801484223;
- psaitong@jm-bio.com
TargetMol Chemicals Inc.
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- 4008200310
- marketing@tsbiochem.com
TargetMol Chemicals Inc.
- Tel
- +17819995354
- marketing@targetmol.com