thielavin B Chemical Properties

storage temp. 

-20°C

solubility 

DMF: soluble; DMSO: soluble; Ethanol: soluble

form 

White to off-white powder.

thielavin B Usage And Synthesis

Description

Thielavin B is a fungal metabolite that contains O-substituted salicylic acid. It inhibits cyclooxygenase, blocking both the conversion of arachidonic acid to Prostaglandin H₂ (PGH₂) and the conversion of PGH₂ to PGE₂ (, IC₅₀s = 40 and 9 μM, respectively). Thielavin B also inhibits the reverse transcriptase of avian myeloblastosis virus, bacterial transglycosylases, and telomerase activity.

Uses

Thielavin B is a fungal metabolite closely related to thielavin A but reported to have a slightly different biochemical profile. Thielavins inhibit glucose-6-phosphatase. Thielavin B is a potent inhibitor of phospholipase C, and inhibits peptidoglycan formation and prostaglandin biosynthesis.

Uses

Thielavin B is a fungal metabolite of?Thielavia terricola that contains O-substituted salicylic acid. It is an inhibitor of viral reverse transcriptase and telomerase.

General Description

Natural product derived from fungal source.

thielavin B(71950-67-9)Related Product Information

• thielocin B3
• DIFFRACTIC ACID
• 4-Benzyloxy-3,5-dimethylbenzoic acid
• thielavin B
• GYROPHORIC ACID
• Methyl 4-acetamido-2-methoxybenzoate
• thielavin A
• 4-BENZYLOXY-3,5-DIMETHYLBENZALDEHYDE
• CHEMBRDG-BB 9070990
• EVERNIC ACID
• METHYL 2,4-DIMETHOXY-6-METHYLBENZOATE
• 2,5-dimethylphenyl 4-methoxybenzoate
• CHEMBRDG-BB 9072034