N,N′-Bis-tert-butoxycarbonylthiourea Chemical Properties

Melting point:

131-135 °C(lit.)

Density 

1.152

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

5.55±0.70(Predicted)

form 

powder to crystal

color 

White to Almost white

InChI

InChI=1S/C11H20N2O4S/c1-10(2,3)16-8(14)12-7(18)13-9(15)17-11(4,5)6/h1-6H3,(H2,12,13,14,15,18)

InChIKey

CSOJECDGWHHWRS-UHFFFAOYSA-N

SMILES

C(C)(C)(C)OC(=O)NC(=S)NC(=O)OC(C)(C)C

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29302000

MSDS

• Language:English Provider:SigmaAldrich

N,N′-Bis-tert-butoxycarbonylthiourea Usage And Synthesis

Chemical Properties

White to off-white solid

Uses

N,N′-Di-Boc-thiourea (N,N′-di-Boc-substituted thiourea), also known as di-Boc-thiourea is a thioacylating agent for preparing thiocarbonyl compounds.
N,N′-Di-Boc-thiourea (di-Boc protected thiourea) may be used as a guanylating agent for the synthesis of guanidines, via guanylation of amines in the presence of Mukaiyama′s reagent as a promoter.

Uses

N,N''-Di(tert-butoxycarbonyl)thiourea is used in the preparation of bis-imidazoline diphenyl derivatives as α1-adrenoceptor antagonists.

N,N′-Bis-tert-butoxycarbonylthiourea(145013-05-4)Related Product Information

• METHYLENE DIURETHANE
• N-BOC THIOUREA 97
• DIMETHYLOLTHIOUREA
• N,N′-Bis-tert-butoxycarbonylthiourea