ALYTESIN
ALYTESIN Basic information
- Product Name:
- ALYTESIN
- Synonyms:
-
- PYR-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
- ALYTESIN
- Alytesin Pyr-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
- GLP-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
- [Gly2, Thr6]-Bombesin
- pGlu-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
- [Gly2, Thr6]-Bombesin, pGlu-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
- GLP-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2: GLP-GRLGTQWAVGHLM-NH2
- CAS:
- 31078-12-3
- MF:
- C68H106N22O17S
- MW:
- 1535.77
- Product Categories:
-
- Neuromedins and related
- Peptide
- Mol File:
- 31078-12-3.mol
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ALYTESIN Chemical Properties
- Density
- 1.47±0.1 g/cm3(Predicted)
- RTECS
- PC4360120
- storage temp.
- −20°C
- pka
- 13.11±0.46(Predicted)
- form
- Solid
- Water Solubility
- Soluble to 1 mg/ml in water
- Sequence
- {Glp}-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
MSDS
- Language:English Provider:SigmaAldrich
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ALYTESIN Usage And Synthesis
Uses
Alytesin, a bombesin-like peptide, is found in extracts of the skin of Alytes obstetricans. Alytesin reduces gastric acid secretion and induces hypertension. Alytesin also induces short-term anorexigenic effects in neonatal chicks[1][2][3]
References
[1] Guglietta A, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. DOI:10.1016/0196-9781(85)90354-7
[2] Erspamer V, et al. Some pharmacological actions of alytesin and bombesin. J Pharm Pharmacol. 1970 Nov;22(11):875-6. DOI:10.1111/j.2042-7158.1970.tb08465.x
[3] Cline MA, et al. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. DOI:10.1016/j.npep.2008.02.004
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