Ethyl 3,3-Diethoxypropionate
Ethyl 3,3-Diethoxypropionate Basic information
- Product Name:
- Ethyl 3,3-Diethoxypropionate
- Synonyms:
-
- Propanoic acid, 3,3-diethoxy-, ethyl ester
- 3,3-DIETHOXYPROPIONIC ACID ETHYL ESTER
- DEPE
- ETHYL 3,3-DIETHOXYPROPANOATE
- ETHYL 3,3-DIETHOXYPROPIONATE
- ETHYL 3,3-DIETHOXYPROPIONATE, TECH., 90%
- 3,3-Diethoxypropanoic acid, ethyl ester
- malonaldehydic acid diethyl acetal ethyl ester
- CAS:
- 10601-80-6
- MF:
- C9H18O4
- MW:
- 190.24
- EINECS:
- 234-223-1
- Product Categories:
-
- Pyridine
- Pharmaceutical Intermediates
- bc0001
- Mol File:
- 10601-80-6.mol
Ethyl 3,3-Diethoxypropionate Chemical Properties
- Melting point:
- 200-202 °C
- Boiling point:
- 92-93 °C/13 mmHg (lit.)
- Density
- 0.978 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.411(lit.)
- Flash point:
- 184 °F
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Liquid
- color
- Clear colorless
- BRN
- 1772110
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C9H18O4/c1-4-11-8(10)7-9(12-5-2)13-6-3/h9H,4-7H2,1-3H3
- InChIKey
- SIALOQYKFQEKOG-UHFFFAOYSA-N
- SMILES
- C(OCC)(=O)CC(OCC)OCC
- LogP
- 2.260 (est)
- CAS DataBase Reference
- 10601-80-6(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
Ethyl 3,3-Diethoxypropionate Usage And Synthesis
Description
Ethyl 3,3-diethoxypropionate is an organic compound that is synthesized from the reaction of diethyl malonate and chloroacetic acid in the presence of a base catalyst. This product has been shown to be an effective inhibitor of mitochondrial cytochrome c oxidase in vitro studies. Ethyl 3,3-diethoxypropionate also has been found to inhibit quinoline derivatives, such as erythromycin and tetracycline, which are involved in bacterial DNA synthesis. Furthermore, this product inhibits β-unsaturated aldehydes and allylation.
Chemical Properties
clear colorless liquid
Uses
Ethyl 3,3-diethoxypropionate participates in the Yb(OTf)3 catalyzed synthesis of dihydropyridines (DHPs).
Synthesis Reference(s)
The Journal of Organic Chemistry, 47, p. 2216, 1982 DOI: 10.1021/jo00132a055
Synthesis, p. 274, 1988 DOI: 10.1055/s-1988-27541
Ethyl 3,3-Diethoxypropionate Preparation Products And Raw materials
Preparation Products
Raw materials
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Ethyl 3,3-Diethoxypropionate(10601-80-6)Related Product Information
- Methyl dimethoxyacetate
- ETHYL TRANS-3-ETHOXYACRYLATE, 98
- Ethyl diethoxyacetate
- METHYL 3,3-DIMETHOXYPROPIONATE
- 2-Chloroadenosine
- 2-HYDROXYADENOSINE
- Propanoicacid,2-formyl-3-oxo-,ethylester
- 2-Hydrazinoadenosine
- Ethyl pyrazole-4-carboxylate
- REGADENOSON
- 2-CHLORO-6-AMINO-9-(2',3',5'-TRI-O-ACETYL-?-D-RIBOFURANOSYL)PURINE
- Furfuryl propionate ester
- 1,1,3-TRIMETHOXYPROPANE
- 1,1,3-TRIETHOXYPROPANE
- Ethyl 3,3-Diethoxypropionate
- Ethyl propionate
- ETHYL 2,2-DIETHOXYPROPIONATE
- 3,3-DIETHOXY-PROPIONIC ACID