Basic information Safety Supplier Related

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2

Basic information Safety Supplier Related

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 Basic information

Product Name:
Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2
Synonyms:
  • ABZ-THR-ILE-NLE-P-NITRO-PHE-GLN-ARG-NH2
  • Anthranilyl-HIV Protease Substrate trifluoroacetate salt Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 trifluoroacetate salt
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-[(2-aminobenzoyl)amino]-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
  • L-Argininamide, N-(2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-
  • 18:PN:EP1382692 SEQID:19 claimed protein
CAS:
133233-38-2
MF:
C43H65N13O11
MW:
940.06
Mol File:
133233-38-2.mol
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 Chemical Properties

form 
Solid
color 
White to off-white
Sequence
{Abz}-Thr-Ile-{Nle}-{p-nitro-Phe}-Gln-Arg-NH2
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 Usage And Synthesis

Uses

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay[1].

References

[1] Porter DJ, et al. Effectors of HIV-1 protease peptidolytic activity. Biochemistry. 2001 Sep 18;40(37):11131-9. DOI:10.1021/bi010418p

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