1-HYDROXYPHENAZINE
1-HYDROXYPHENAZINE Basic information
- Product Name:
- 1-HYDROXYPHENAZINE
- Synonyms:
-
- 1-phenazinol
- alpha-hydroxyphenazine
- hemipyocyanin
- hemipyocyanine
- pyoxanthose
- Hydroxyphenazine
- 1-HYDROXYPHENAZINE 95+%
- Phenazin-1-ol
- CAS:
- 528-71-2
- MF:
- C12H8N2O
- MW:
- 196.2
- Mol File:
- 528-71-2.mol
1-HYDROXYPHENAZINE Chemical Properties
- Melting point:
- 158°C
- Boiling point:
- 333.09°C (rough estimate)
- Density
- 1.1788 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml
- pka
- 6.62±0.30(Predicted)
- form
- powder to crystaline
- color
- Light yellow to Brown
- Merck
- 14,4645
Safety Information
- Safety Statements
- 22-24/25
- RTECS
- SG1647000
- HS Code
- 2933.99.9701
1-HYDROXYPHENAZINE Usage And Synthesis
Uses
Hemipyocyanine (1-hydroxyphenazine) is a simple phenazine metabolite produced by several species of Pseudomonas and Streptomyces. Hemipyocyanine exhibits broad spectrum activity with weak antibacterial, antifungal and antiviral activity. In the search for novel actives, hemipyocyanine and related phenazines are important dereplication standards to eliminate leads due to high amounts of weakly potent actives. Hemipyocyanine plays an important role in the biocontrol of plant diseases by some Pseudomonas strains.
Uses
Hemipyocyanine is a phenazine metabolite and important dereplication standard.
Definition
ChEBI: A phenazine carrying a hydroxy substituent at the 1-position.
Purification Methods
Purify the hydroxyphenazine by chromatography on acidic alumina with *benzene/ether and recrystallise it from aqueous EtOH, *benzene/heptane, then sublime it at 140o/1.5mm. [UV, IR: Badger et al. J Chem Soc 3204 1951, Hegedüs Helv Chim Acta 33 746 1950, Beilstein 23 II 360, 23 III/IV 2753.]
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1-HYDROXYPHENAZINE(528-71-2)Related Product Information
- 2-hydroxyphenazine
- 1-Amino-2-hydroxyphenazine
- 2-AMINO-3-HYDROXYPHENAZINE
- 1,1'-Methylenebis[2-hydroxyphenazine]
- 4-Hydroxyphenazine 5,10-dioxide
- 1-Hydroxyphenazine 5-oxide
- 2-hydroxyphenazine-1-carboxylic acid
- 1-HYDROXYPHENAZINE
- 1,6-Dihydroxy-2-chlorophenazine
- myxin
- Cuprimyxin
- LOMOFUNGIN
- 1-Methoxy-5-methylphenazinium methyl sulfate
- 3-Hydroxy-L-valine (6-carboxy-4-methoxy-1-phenazinyl)methyl ester
- 6,9-DIMETHOXY-PHENAZINE-1-CARBOXYLIC ACID
- 1-METHOXYPHENAZINE