Basic information Safety Supplier Related

1-HYDROXYPHENAZINE

Basic information Safety Supplier Related

1-HYDROXYPHENAZINE Basic information

Product Name:
1-HYDROXYPHENAZINE
Synonyms:
  • 1-phenazinol
  • alpha-hydroxyphenazine
  • hemipyocyanin
  • hemipyocyanine
  • pyoxanthose
  • Hydroxyphenazine
  • 1-HYDROXYPHENAZINE 95+%
  • Phenazin-1-ol
CAS:
528-71-2
MF:
C12H8N2O
MW:
196.2
Mol File:
528-71-2.mol
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1-HYDROXYPHENAZINE Chemical Properties

Melting point:
158°C
Boiling point:
333.09°C (rough estimate)
Density 
1.1788 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml
pka
6.62±0.30(Predicted)
form 
powder to crystaline
color 
Light yellow to Brown
Merck 
14,4645
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Safety Information

Safety Statements 
22-24/25
RTECS 
SG1647000
HS Code 
2933.99.9701
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1-HYDROXYPHENAZINE Usage And Synthesis

Uses

Hemipyocyanine (1-hydroxyphenazine) is a simple phenazine metabolite produced by several species of Pseudomonas and Streptomyces. Hemipyocyanine exhibits broad spectrum activity with weak antibacterial, antifungal and antiviral activity. In the search for novel actives, hemipyocyanine and related phenazines are important dereplication standards to eliminate leads due to high amounts of weakly potent actives. Hemipyocyanine plays an important role in the biocontrol of plant diseases by some Pseudomonas strains.

Uses

Hemipyocyanine is a phenazine metabolite and important dereplication standard.

Definition

ChEBI: A phenazine carrying a hydroxy substituent at the 1-position.

Purification Methods

Purify the hydroxyphenazine by chromatography on acidic alumina with *benzene/ether and recrystallise it from aqueous EtOH, *benzene/heptane, then sublime it at 140o/1.5mm. [UV, IR: Badger et al. J Chem Soc 3204 1951, Hegedüs Helv Chim Acta 33 746 1950, Beilstein 23 II 360, 23 III/IV 2753.]

1-HYDROXYPHENAZINESupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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TCI (Shanghai) Development Co., Ltd.
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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isenchem@163.com