2,6,6-TRIMETHYL-1-CYCLOHEXENE-1-ACETALDEHYDE Chemical Properties

Boiling point:

58-59 °C/0.4 mmHg (lit.)

Density 

0.941 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.485(lit.)

FEMA 

3474 | 2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-ACETALDEHYDE

Flash point:

191 °F

storage temp. 

2-8°C

Odor

at 10.00 % in dipropylene glycol. camphoreous cooling woody medicinal oily berry orris soapy

Odor Type

camphoreous

JECFA Number

978

LogP

3.94

EPA Substance Registry System

1-Cyclohexene-1-acetaldehyde, 2,6,6-trimethyl- (472-66-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

2,6,6-TRIMETHYL-1-CYCLOHEXENE-1-ACETALDEHYDE Usage And Synthesis

Uses

2,6,6-Trimethyl-1-cyclohexene-1-acetaldehyde can be used as a starting material to prepare:

• (±)-Aeginetolide by oxidation in the presence of meta-chloroperoxybenzoic acid (m-CPBA).
• (±)-Dihydroactinidiolide (a C₁₁-terpenic lactone) via dehydration of key intermediate aeginetolide.

It can also be used as a key intermediate to synthesize drimane-related sesquiterpenes and substituted retinoic acid analogs.

Definition

ChEBI: 2,6,6-Trimethyl-1-cyclohexen-1-acetaldehyde is an aldehyde.

Taste threshold values

Taste characteristics at 15 ppm: cooling, woody, oily, soapy, citrus with a berry, orris-like nuance.

2,6,6-TRIMETHYL-1-CYCLOHEXENE-1-ACETALDEHYDE(472-66-2)Related Product Information

• 7-EPI-10-DEACETYL-TAXOL
• Deacetyltaxol
• 10-DEACETYLCEPHALOMANNINE
• Docetaxel
• Baccatine III
• 2,6,6-TRIMETHYL-1-CYCLOHEXENE-1-ACETALDEHYDE
• 10-Deacetylbaccatin III
• Cephalomannine
• Paclitaxel
• 7-EPI-TAXOL
• PACLITAXEL, [3H(G)]
• 2'-ACETYLTAXOL
• 2,6,6-trimethyl-2-cyclohexene-1-acetaldehyde
• XYLOSYLTAXOL
• PACLITAXEL-[BENZOATE RING-UL-14C]
• PACLITAXEL C
• 10-DEACETYLTAXOL C
• 10-DEACETYL-7-XYLOSYLTAXOL