4-NITRO-2-THIOPHENECARBOXYLIC ACID Chemical Properties

Melting point:

154 °C

Boiling point:

383.3±27.0 °C(Predicted)

Density 

1.676±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

pka

2.81±0.10(Predicted)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HS Code 

29349990

4-NITRO-2-THIOPHENECARBOXYLIC ACID Usage And Synthesis

Chemical Properties

Off white solid

Uses

4-Nitro-2-thiophenecarboxylic Acid, is an intermediate in the synthesis of pharmaceutical compounds. It is utilized in the preparation of highly potent and selective hetaryl ureas as integrin αVβ3-Receptor antagonists.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 577, 1955 DOI: 10.1021/ja01608a017

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