4-Nitrophenylboronic acid Chemical Properties

Melting point:

285-290°C (dec.)

Boiling point:

373.7±44.0 °C(Predicted)

Density 

1.40±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml

pka

7.04±0.10(Predicted)

form 

Crystalline Powder

color 

White to yellow

Water Solubility 

Slightly soluble in water.

InChIKey

NSFJAFZHYOAMHL-UHFFFAOYSA-N

CAS DataBase Reference

24067-17-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

26-36/37/39-24/25

WGK Germany 

3

Hazard Note 

Harmful

HS Code 

29319090

4-Nitrophenylboronic acid Usage And Synthesis

Description

4-Nitrobenzeneboronic acid is an arylboronic acid building block that has been used in the synthesis of phenols.

Chemical Properties

White to brown powder or crystal

Uses

4-Nitrophenylboronic Acid is a useful synthetic intermediate. It is a reagent used for ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings, Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines and Diels-Alder or C-H activation reactions.

Uses

Reagent used for

• Ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings
• Ruthenium catalyzed direct arylation of benzylic sp³ carbons of acyclic amines
• Diels-Alder or C-H activation reactions
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulations
• N-arylation of phenylurea using copper acetylacetonate catalyst
• Environmentally benign one-pot synthesis through a double arylation process
• Copper-mediated cyanations
• copper-catalyzed arylations
• Regioselective glycosylations
• Suzuki couplings followed by arylations
• X-ray absorption on rhodium-grafted hydrotalcite catalyst for heterogeneous 1,4-addition reaction of organoboron reagents to electron deficient olefins

• Combretastatin analogs as potential antitumor agents
• Human immunodeficiency virus (HIV) protease inhibitors with antiviral activities against drug-resistant viruses

Uses

suzuki reaction

4-Nitrophenylboronic acid(24067-17-2)Related Product Information

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