Phenylacetone Chemical Properties

Melting point:

-15 °C

Boiling point:

216 °C

Density 

1.003 g/mL at 20 °C(lit.)

refractive index 

1.5155-1.5175

Flash point:

83°C

storage temp. 

Controlled Substance, -20°C Freezer

solubility 

DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Methanol: 50 mg/ml

Water Solubility 

Insoluble

BRN 

742120

LogP

1.440

CAS DataBase Reference

103-79-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzyl methyl ketone(103-79-7)

EPA Substance Registry System

2-Propanone, 1-phenyl- (103-79-7)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

UC3500100

HS Code 

29143910

Hazardous Substances Data

103-79-7(Hazardous Substances Data)

Toxicity

LD50 intraperitoneal in mouse: 540mg/kg

DEA Controlled Substances

CSCN: 8501
CSA SCH: Schedule II
NARC: No

MSDS

• Language:English Provider:Phenylacetone
• Language:English Provider:SigmaAldrich

Phenylacetone Usage And Synthesis

Description

Phenylacetone (exempt preparation) (Item No. 16444) is an analytical reference standard categorized as a precursor in the synthesis of amphetamine and methamphetamine. Phenylacetone is regulated as a Schedule II compound in the United States. Phenylacetone (exempt preparation) (Item No. 16444) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

1-Phenyl-2-propanone is a colorless liquid with a pleasant odor; it is insoluble in water and soluble in organic solvents.

Uses

A metabolite of Lisdexamfetamine dimesylate. 1-Phenyl-2-propanone is used as an intermediate for the synthesis of pharmaceuticals, e.g., Prenylamine, a coronary vasodilator (Hoechst) .

Uses

In organic synthesis; production of benzyl radicals by photolysis.

Definition

ChEBI: Phenylacetone is a propanone that is propan-2-one substituted by a phenyl group at position 1. It is a member of propanones and a methyl ketone.

Production Methods

1-Phenyl-2-propanone is produced by catalytic ketonization of phenylacetic acid with acetic acid over an alumina-supported cerium oxide catalyst at 400 – 500℃. It may also be produced by the rearrangement of phenylpropylene oxide on zeolites or oxidation of 2-phenylpropanol.

Phenylacetone(103-79-7)Related Product Information

• Benzyl chloride
• Benzyl isocyanate
• Benzyl benzoate
• Benzyl alcohol
• Methyl salicylate
• Thiophanate-methyl
• PHENYL VALERATE
• Citric acid monohydrate
• Diphenyl ether
• Phenyl salicylate
• Benzyl nicotinate
• PHENYL RESIN
• Methyl
• Phenylacetone
• 2-BROMO-2-PHENYLACETOPHENONE
• 2,5-DIPHENYL-P-BENZOQUINONE
• Phenanthrenequinone
• Tetraphenylcyclopentadienone