1-CBZ-2-PIPERIDINECARBOXYLIC ACID Chemical Properties

Melting point:

110 °C(Solv: ethanol (64-17-5))

Boiling point:

443.9±45.0 °C(Predicted)

Density 

1.265±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

form 

powder to crystal

pka

4.01±0.20(Predicted)

color 

White to Almost white

Safety Information

Risk Statements 

20/21/22

Safety Statements 

24/25-36/37/38-29/56-41-45-3/7/9

HS Code 

29333990

1-CBZ-2-PIPERIDINECARBOXYLIC ACID Usage And Synthesis

Chemical Properties

White solid

Uses

1,?2-?Piperidinedicarboxyl?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer.

1-CBZ-2-PIPERIDINECARBOXYLIC ACID(28697-07-6)Related Product Information

• 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
• N-CBZ-3-PIPERIDINECARBOXYLIC ACID
• 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
• 1-CBZ-4-PIPERIDINECARBOXYLIC ACID,N-CBZ-4-PIPERIDINECARBOXYLIC ACID
• N-CBZ-4-PIPERIDINECARBOXYLIC ACID METHYL ESTER
• 4-METHYL-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER
• (R)-(+)-1-Cbz-2-piperidinecarboxylic acid, 97%+D93,(R)-(+)-1-CBZ-2-PIPERIDINECARBOXYLIC ACID
• 4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 2-METHYL ESTER
• (S)-(-)-1-Cbz-2-piperidinecarboxylic acid, 97%
• (3S,4AS,8AS)-2-CARBOBENZYLOXY-DECAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID
• CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 2-METHYL ESTER
• 4-ISOPROPYL-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER
• N-CBZ-2-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER
• 2-METHYL-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER
• N-CBZ-3-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER
• 1-[(4-NITROBENZYLOXY)CARBONYL]-PIPERIDINE-2-CARBOXYLIC ACID
• CBZ-(2S, 4R)-4-HYDROXY-PIPERIDINE-2-CARBOXYLIC ACID METHYL ESTER
• 4-METHYLAMINO-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 2-METHYL ESTER