CYCLEANINE
CYCLEANINE Basic information
- Product Name:
- CYCLEANINE
- Synonyms:
-
- 8,11:20,23-DIETHENO-1H,12H-[1,10]DIOXACYCLOOCTADECINO[2,3,4-IJ:11,12,13-I'J']DIISOQUINOLINE,2,3,12A,13,14,15,24,24A-OCTAHYDRO-5,6,17,18-TETRAMETHOXY-1,13-DIMETHYL-, [12AR-(12AR*,24AR*)]-
- (1R)-2,2'-Dimethyl-6,6',7,7'-tetramethoxy-7,18:11',18-diseco-8,18:12',18-dicyclotubocuraran
- 8,11:20,23-Dietheno-1H,12H-(1,10)dioxacyclooctadecino(2,3,4-ij:11,12,13-I'J')diisoquinoline, 2,3,12A,13,14,15,24,24A-octahydro-1,13-dimethyl-5,6,17,18-tetramethoxy-, (12ar-(12ar*,24ar*))-
- Cycleanine (6ci,7ci,8ci)
- Dimethylisochondodendrine
- o,o-Dimethylisochondodendrin
- CYCLEANINE
- CYCLEANINE: 8,11:20,23-DIETHENO-1H,12H-[1,10]DIOXACYCLOOCTADECINO[2,3,4-IJ:11,12,13-I'J']DIISOQUINOLINE,2,3,12A,13,14,15,24,24A-OCTAHYDRO-5,6,17,18-TETRAMETHOXY-1,13-DIMETHYL-, [12AR- (12AR*,24AR*)]-,
- CAS:
- 518-94-5
- MF:
- C38H42N2O6
- MW:
- 622.75
- Mol File:
- 518-94-5.mol
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CYCLEANINE Chemical Properties
- Melting point:
- 272-273 °C
- Boiling point:
- 691.6±55.0 °C(Predicted)
- Density
- 1.172±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, away from moisture and light
- solubility
- Acetone: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
- form
- A solid
- pka
- 7.56±0.20(Predicted)
- color
- White to off-white
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CYCLEANINE Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the white herbs, geohuai, light leaf geohuai, southern rotundo, Sichuan rotundo, wah's monohuai, tin sheng vine.
Uses
Cycleanine is an alkaloid obtained from the Triclisia subcordata Oliv (Menispermeaceae) which is a medicinal plant used to treat various diseases in West Africa. Displays in-vitro anti-ovarian cancer activity.
Definition
ChEBI: Cycleanine is a member of isoquinolines and a bisbenzylisoquinoline alkaloid.
in vivo
Cycleanine inhibits the KCl-induced contraction of rabbit aortic rings with an IC50 of 0.8 nM[1].
IC 50
L-type calcium channel
CYCLEANINESupplier
Hangzhou Yuhao Chemical Technology Co., Ltd
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- 0571-82693216
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Chengdu Biopurify Phytochemicals Ltd.
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- +86-028-82633397 18982077548
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Chengdu Climax Biotech Co., Ltd.
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- 028-83311324 1278112614
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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- 400-6206333 13167063860
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Shanghai Tauto Biotech Co., Ltd.
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- 021-51320588
- tauto@tautobiotech.com