AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2
AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2 Basic information
- Product Name:
- AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2
- Synonyms:
-
- SH2 DOMAIN LIGAND (1)
- AC-D-PY-VPML-NH2
- AC-DY(PO3H2)VPML-NH2
- AC-ASP-PTYR-VAL-PRO-MET-LEU-NH2
- AC-ASP-TYR(H2PO3)-VAL-PRO-MET-LEU-NH2
- AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2
- AC-ASP-TYR: PO3H2-VAL-PRO-MET-LEU-NH2 [AC-D-Y: PO3H2-VPML-NH2]
- L-Leucinamide, N-acetyl-L-α-aspartyl-O-phosphono-L-tyrosyl-L-valyl-L-prolyl-L-methionyl-
- CAS:
- 157382-69-9
- MF:
- C36H56N7O13PS
- MW:
- 857.91
- Product Categories:
-
- peptide
- Mol File:
- Mol File
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AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2 Chemical Properties
- Density
- 1.346±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 1.27±0.30(Predicted)
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AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2 Usage And Synthesis
Uses
Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is the SH2 domain ligand. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal[1].
References
[1] Burke TR Jr, et al. Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors. Biochemistry. 1994 May 31;33(21):6490-4. DOI:10.1021/bi00187a015
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