ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > GW791343 (HCl)
GW791343 (HCl)
GW791343 (HCl) Basic information
- Product Name:
- GW791343 (HCl)
- Synonyms:
-
- GW791343 (HCl)
- 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamidetrihydrochloride
- GW 791343 hydrochloride
- 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]acetamide hydrochloride
- GW 791343
- GW 791343 dihydrochloride
- GW791343 (dihydrochloride)
- 2-((3,4-difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide dihydrochloride
- CAS:
- 1019779-04-4
- MF:
- C20H24F2N4O
- MW:
- 374.4275664
- EINECS:
- 200-258-5
- Product Categories:
-
- P2X7 allosteric modulator.
- Mol File:
- 1019779-04-4.mol
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GW791343 (HCl) Chemical Properties
- storage temp.
- Desiccate at RT
- solubility
- H2O : 100 mg/mL (223.54 mM; Need ultrasonic)DMSO : 20 mg/mL (44.71 mM; Need ultrasonic)
- form
- Powder
- color
- White to off-white
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GW791343 (HCl) Usage And Synthesis
Uses
GW 791343 DTrihydrochloride is a P2X7 receptor antagonist that acts as an allosteric inhibitor, exhibiting negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the rat P2X7 receptor. P2X7 receptor is responsible for the presence of inflammatory cells, regulated by extracellular ATP.
Uses
GW 791343 Hydrochloride is a P2X7 allosteric modulator.
IC 50
P2X7 Receptor: 6.9-7.2 (pIC50)
GW791343 (HCl)Supplier
J & K SCIENTIFIC LTD.
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- 18210857532; 18210857532
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3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
VDM Biochemicals
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- 0330-2528181
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Nanjing Chemlin Chemical Co., Ltd
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- 025-83697070 13913916777;
- info@chemlin.com.cn
Chengdu NoVi Biotechnology Co., Ltd.
- Tel
- 028-81458053
- novibiotech@163.com sales@novi-biotech.com