HeMatoporphyrin MonoMethyl ether Chemical Properties

Boiling point:

1123.6±65.0 °C(Predicted)

Density 

1.287

storage temp. 

4°C, protect from light

solubility 

DMSO : 62.5 mg/mL (102.00 mM; Need ultrasonic)

form 

Solid

color 

Brown to reddish brown

InChIKey

HWEFINLVIQZVMZ-OYYVZGGRSA-N

SMILES

C1=C2N=C(C=C3NC(=CC4=NC(=CC5NC1=C(C)C=5CCC(O)=O)C(CCC(O)=O)=C4C)C(C(OC)C)=C3C)C(C(O)C)=C2C |c:0,4,7,11|

HeMatoporphyrin MonoMethyl ether Usage And Synthesis

Uses

Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and research of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma[1].

References

[1] Ding X, et al. Hematoporphyrin monomethyl ether photodynamic damage on HeLa cells by means of reactive oxygen species production and cytosolic free calcium concentration elevation. Cancer Lett. 2004;216(1):43-54. DOI:10.1016/j.canlet.2004.07.005

HeMatoporphyrin MonoMethyl ether(148471-91-4)Related Product Information

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