5,6-DiHETE Chemical Properties

Boiling point:

515.8±50.0 °C(Predicted)

Density 

1.040±0.06 g/cm3(Predicted)

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml

pka

4.68±0.10(Predicted)

5,6-DiHETE Usage And Synthesis

Description

Eicosapentaenoic acid (EPA; ) is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils. EPA is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases. (±)5(6)-DiHETE is a possible metabolite produced from EPA following epoxidation of the α-5 double bond. The biological activity of (±)5(6)-DiHETE has not been documented.

Definition

ChEBI: 5,6-DiHETE is a polyunsaturated fatty acid and a hydroxy fatty acid.