PF-232798
PF-232798 Basic information
- Product Name:
- PF-232798
- Synonyms:
-
- PF-232798
- PF 00232798
- PF00232798
- PF-00232798
- PF 232798,PF232798
- Acetamide, N-[(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-[4,5,6,7-tetrahydro-2-methyl-5-(2-methyl-1-oxopropyl)-1H-imidazo[4,5-c]pyridin-1-yl]-8-azabicyclo[3.2.1]oct-8-yl]propyl]-
- N-[(1S)-1-(3-Fluorophenyl)-3-[(1R,5S)-3-[2-methyl-5-(2-methylpropanoyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridin-1-yl]-8-azabicyclo[3.2. 1]octan-8-yl]propyl]acetamide
- CAS:
- 849753-15-7
- MF:
- C29H40FN5O2
- MW:
- 509.6586032
- Mol File:
- 849753-15-7.mol
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PF-232798 Chemical Properties
- Boiling point:
- 765.2±60.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- pka
- 15.39±0.46(Predicted)
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PF-232798 Usage And Synthesis
Uses
PF-232798 is an orally active CCR5 antagonist with anti-HIV effects[1].
References
[1] Ya Zhu, et al. Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5. Acta Pharmacol Sin. 2019 Apr;40(4):563-568. DOI:10.1038/s41401-018-0054-2
PF-232798Supplier
ShangHai Caerulum Pharma Discovery Co., Ltd.
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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.
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Biosynth Biological Technology (Suzhou) Co Ltd
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