ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > LHW090-A7
LHW090-A7
LHW090-A7 Basic information
- Product Name:
- LHW090-A7
- Synonyms:
-
- LHW090-A7
- (alphaS)-3'-Chloro-alpha-[[(1S)-2-ethoxy-1-methyl-2-oxoethyl]amino][1,1'-biphenyl]-4-propanoic acid
- EOS-61103
- (S)-3-(3'-Chloro-[1,1'-biphenyl]-4-yl)-2-(((S)-1-ethoxy-1-oxopropan-2-yl)amino)propanoic acid
- Sodium (2S)-3-(3'-chloro-[1,1'-biphenyl]-4-yl)-2-{[(2S)-1-ethoxy-1-oxopropan-2-yl]amino}propanoate
- CS-2208
- [1,1'-Biphenyl]-4-propanoic acid, 3'-chloro-α-[[(1S)-2-ethoxy-1-methyl-2-oxoethyl]amino]-, (αS)-
- (αS)-3'-Chloro-α-[[(1S)-2-ethoxy-1-methyl-2-oxoethyl]amino][1,1'-biphenyl]-4-propanoic acid
- CAS:
- 1308256-94-1
- MF:
- C20H22ClNO4
- MW:
- 375.85
- Mol File:
- 1308256-94-1.mol
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LHW090-A7 Chemical Properties
- solubility
- DMSO: 5 mg/ml
Ethanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml - InChI
- InChI=1/C20H22ClNO4/c1-3-26-20(25)13(2)22-18(19(23)24)11-14-7-9-15(10-8-14)16-5-4-6-17(21)12-16/h4-10,12-13,18,22H,3,11H2,1-2H3,(H,23,24)/t13-,18-/s3
- InChIKey
- PWYAUIUPDMSWJH-CODVNQPLNA-N
- SMILES
- C(O)(=O)[C@@H](N[C@@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC(Cl)=C2)C=C1 |&1:3,5,r|
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LHW090-A7 Usage And Synthesis
Description
LHW090-A7 is a compound developed as an inhibitor of neutral endopeptidase (NEP), an enzyme responsible for the metabolic inactivation of enkephalins. Inhibitors of NEP have been shown to increase plasma levels of endogenous atrial natriuretic peptides and, as such, are expected to induce natriuretic and diuretic effects.
References
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
LHW090-A7Supplier
Shanghai Taibao Pharmaceutical Technology Co., Ltd. Gold
- Tel
- 13816752554
- 1745533547@qq.com
Shanghai Boyle Chemical Co., Ltd.
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- sales@boylechem.com
AdooQ Bioscience CHINA
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- 025-58849295 18951903616;
- info@adooq.cn
Shanghai Lollane Biological Technology Co.,Ltd.
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- 021-52996696,15000506266 15000506266
Nanjing Chempioneer Pharmaceutical Co., Ltd.
- Tel
- 18068075658
- sales@chempioneer.com