Basic information Safety Supplier Related

STROPHANTHIDIN

Basic information Safety Supplier Related

STROPHANTHIDIN Basic information

Product Name:
STROPHANTHIDIN
Synonyms:
  • 19-oxo-cardogenen-(20:22)-triol-(3-beta,5,14)
  • 3,5,14-trihydroxy-19-oxo-,(3-beta,5-beta)-card-20(22)-enolid
  • 3,5,14-trihydroxy-19-oxocard-20(22)-enolide
  • 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolid
  • 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolide
  • 3-beta,5,14-trioxy-19-oxo-carden-(20:22)-olid
  • 3-beta,5,14-trioxy-19-oxo-digen-(20:22)-olid
  • 5-beta-hydroxy-19-oxodigitoxigenin
CAS:
66-28-4
MF:
C23H32O6
MW:
404.5
EINECS:
200-626-6
Product Categories:
  • Sterol Lipids
  • Aldehydes
  • Biochemicals and Reagents
  • Building Blocks
  • C13-C60
  • Carbonyl Compounds
  • Chemical Synthesis
  • Conjugates
  • Lipids
  • Organic Building Blocks
Mol File:
66-28-4.mol
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STROPHANTHIDIN Chemical Properties

Melting point:
169°C
alpha 
D25 +43.1° (c = 2.8 in methanol)
Boiling point:
446.1°C (rough estimate)
Density 
1.432±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.4593 (estimate)
storage temp. 
-20°C
solubility 
ethanol: complete50mg/mL, clear, colorless to yellow
pka
13.92±0.70(Predicted)
form 
Solid
color 
White to off-white
optical activity
+43.125 (c 2.8, methanol)
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Safety Information

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
FH5425000
Toxicity
LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel)

MSDS

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STROPHANTHIDIN Usage And Synthesis

Uses

cardiotonic

Uses

Strophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.3

Definition

ChEBI: Strophanthidin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid, a 5beta-hydroxy steroid, a 19-oxo steroid, a member of cardenolides and a steroid aldehyde. It is functionally related to a 5beta-cardanolide.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2

STROPHANTHIDINSupplier

Huzhou ZhanShu Biotechnology Co.,Ltd Gold
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0572-8889530 18167260939
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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market03@meryer.com
Beijing HwrkChemical Technology Co., Ltd
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010-89508211 18501085097
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Spectrum Chemical Manufacturing Corp.
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021-021-021-67601398-809-809-809 15221380277
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marketing_china@spectrumchemical.com
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
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