STROPHANTHIDIN
STROPHANTHIDIN Basic information
- Product Name:
- STROPHANTHIDIN
- Synonyms:
-
- 19-oxo-cardogenen-(20:22)-triol-(3-beta,5,14)
- 3,5,14-trihydroxy-19-oxo-,(3-beta,5-beta)-card-20(22)-enolid
- 3,5,14-trihydroxy-19-oxocard-20(22)-enolide
- 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolid
- 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolide
- 3-beta,5,14-trioxy-19-oxo-carden-(20:22)-olid
- 3-beta,5,14-trioxy-19-oxo-digen-(20:22)-olid
- 5-beta-hydroxy-19-oxodigitoxigenin
- CAS:
- 66-28-4
- MF:
- C23H32O6
- MW:
- 404.5
- EINECS:
- 200-626-6
- Product Categories:
-
- Sterol Lipids
- Aldehydes
- Biochemicals and Reagents
- Building Blocks
- C13-C60
- Carbonyl Compounds
- Chemical Synthesis
- Conjugates
- Lipids
- Organic Building Blocks
- Mol File:
- 66-28-4.mol
STROPHANTHIDIN Chemical Properties
- Melting point:
- 169°C
- alpha
- D25 +43.1° (c = 2.8 in methanol)
- Boiling point:
- 446.1°C (rough estimate)
- Density
- 1.432±0.06 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.4593 (estimate)
- storage temp.
- -20°C
- solubility
- ethanol: complete50mg/mL, clear, colorless to yellow
- pka
- 13.92±0.70(Predicted)
Safety Information
- Hazard Codes
- T+
- Risk Statements
- 26/27/28
- Safety Statements
- 22-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 1
- WGK Germany
- 3
- RTECS
- FH5425000
- Toxicity
- LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel)
MSDS
- Language:English Provider:SigmaAldrich
STROPHANTHIDIN Usage And Synthesis
Uses
cardiotonic
Uses
Strophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.3
Definition
ChEBI: Strophanthidin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid, a 5beta-hydroxy steroid, a 19-oxo steroid, a member of cardenolides and a steroid aldehyde. It is functionally related to a 5beta-cardanolide.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2
STROPHANTHIDINSupplier
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- 021-021-021-67601398-809-809-809 15221380277
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STROPHANTHIDIN(66-28-4)Related Product Information
- 3-ACETYL STROPHANTHIDIN,ACETYL-STROPHANTHIDIN, 3-,ACETYL-STROPHANTHIDIN,strophanthidin3-acetat
- K-STROPHANTHIDIN-D-CYMAROSIDE,K-STROPHANTHIDIN-D-CYMAROSIDE
- k-strophanthidin-gamm
- OUABAGENIN
- STROPHANTHIDIN ALPHA-L-RHAMNOPYRANOSIDE,STROPHANTHIDIN A-L-RHAMNOPYRANOSIDE,6-deoxy-strophanthidin-alpha-l-mannopyranosi
- STROPHANTHIDIN 3BETA-DIGITOXOSIDE,STROPHANTHIDIN 3BETA-DIGITOXOSIDE,Erisimin, Strophanthidin 3β-digitoxoside,Erisimin, Strophanthidin 3β-digitoxoside
- STROPHANTHIDIN(RG),STROPHANTHIDIN(RG)
- ACETYL-STROPHANTHIDIN, 3-(RG),ACETYL-STROPHANTHIDIN, 3-(RG)
- strophanthidin-3-tosyloxyacetate,strophanthidin-3-tosyloxyacetate
- Strophanthidin monoglucoside,Strophanthidin monoglucoside
- Strophanthidin 3-[(dipropylamino)acetate],Strophanthidin 3-[(dipropylamino)acetate]
- Acetyl-k-strophanthidin,Acetyl-k-strophanthidin
- Strophanthidin bromoacetate,strophanthidin 3-bromoacetate,strophanthidin 3-bromoacetate,Strophanthidin bromoacetate
- Bis(strophanthidin) hydrate,Bis(strophanthidin) hydrate
- Strophanthidin (Corchorin),Strophanthidin (Corchorin)
- Strophanthidin 3-[(diethylamino)acetate],Strophanthidin 3-[(diethylamino)acetate]
- Strophanthidin digitoxoside,Strophanthidin digitoxoside
- Strophanthidin 3-[(dimethylamino)acetate],Strophanthidin 3-[(dimethylamino)acetate]