Anti-hMAD1
Anti-hMAD1 Basic information
- Product Name:
- Anti-hMAD1
- Synonyms:
-
- Anti-MAD1L1 antibody produced in rabbit
- Anti-Mitotic spindle assembly checkpoint protein
- Anti-Mitotic arrest deficient-like protein 1
- Anti-MAD1-like 1
- Anti-HsMAD1
- Anti-hMAD1
- Anti-MAD1
- Anti-Mitotic checkpoint MAD1 protein-homolog
- MW:
- 0
- Mol File:
- Mol File
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Anti-hMAD1 Chemical Properties
- storage temp.
- -20°C
- form
- buffered aqueous glycerol solution
- biological source
- rabbit
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Anti-hMAD1 Usage And Synthesis
Biological Activity
Mitotic spindle assembly checkpoint protein MAD1 is a protein encoded by the MAD1L1 gene in humans and is mapped to human chromosome 7p22. It is essential for mitotic arrest and has an additional function in promoting the checkpoint. Alteration in its expression is associated with chromosomal instability and might be used as a prognostic biomarker for breast cancer. Its expression in nuclei is a predictive biomarker of contraindication to pacilitaxel treatment in breast cancer. The protein may act as a potential target for sensitizing cancer cells to redox-cycling drugs.