RO 25-6981 HYDROCHLORIDE
RO 25-6981 HYDROCHLORIDE Basic information
- Product Name:
- RO 25-6981 HYDROCHLORIDE
- Synonyms:
-
- [R-(R*,S*)]-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL HYDROCHLORIDE
- 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol
- [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride
- [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate
- Ro 25-6981 hydrochloride hydrate
- Ro 25 6981 HCl
- Ro 256981 HCl
- Ro 25-6981 HCl
- CAS:
- 919289-58-0
- MF:
- C22H30ClNO2
- MW:
- 375.93
- Product Categories:
-
- Glutamate receptor
- Mol File:
- 919289-58-0.mol
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RO 25-6981 HYDROCHLORIDE Chemical Properties
- solubility
- H2O: 2 mg/mL
- form
- powder
- color
- white
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MSDS
- Language:English Provider:SigmaAldrich
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RO 25-6981 HYDROCHLORIDE Usage And Synthesis
Uses
Ro 25-6981 hydrochloride hydrate has been used:
- as NR2B antagonist for microinjecting rats to study the contribution of NR2B- and NR2A-containing N-methyl-D-aspartate receptors (NMDARs) to the formation of trace and contextual memory in prefrontal cortex (PL)
- as NR2B antagonist to study the effect of the protein expression of hypoxic-ischemic injury NMDAR subunits 2A and 2B in the SVZ of neonatal rats
- to induce deleterious effects upon memory consolidation and long-term potentiation (LTP) generation in the hippocampus
Biochem/physiol Actions
Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit.
RO 25-6981 HYDROCHLORIDESupplier
Sigma-Aldrich
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