3-HYDROXYANTHRANILIC ACID Chemical Properties

Melting point:

240 °C (dec.)(lit.)

Boiling point:

276.03°C (rough estimate)

Density 

1.3585 (rough estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly, Heated)

form 

Liquid or Low Melting Solid

pka

pK1: 2.5(+1);pK2: 5.192(0);pK3: 10.118(OH) (25°C)

color 

Clear colorless to white to yellow to orange

CAS DataBase Reference

548-93-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-40

Safety Statements 

22-26-36

WGK Germany 

3

RTECS 

DG2625000

HS Code 

29225000

Hazardous Substances Data

548-93-6(Hazardous Substances Data)

MSDS

• Language:English Provider:SigmaAldrich

3-HYDROXYANTHRANILIC ACID Usage And Synthesis

Uses

3-Hydroxyanthranilic Acid is one of the tryptophan’s metabolites along the kynurenine pathway. 3-Hydroxyanthranilic Acid has been shown to induce apoptosis in T cells.

Definition

ChEBI: An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.

Purification Methods

The hydrochloride has m 227o (from dilute HCl). [Beilstein 14 H 587, 14 III 1463, 14 IV 2071.] Possible carcinogen.

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