2-AMINO-3-METHOXYBENZOIC ACID Chemical Properties

Melting point:

169-170 °C (lit.)

Boiling point:

333.9±27.0 °C(Predicted)

Density 

1.303±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

4.82±0.10(Predicted)

form 

Powder

color 

White to yellow to brown

CAS DataBase Reference

3177-80-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HS Code 

29225090

MSDS

• Language:English Provider:SigmaAldrich

2-AMINO-3-METHOXYBENZOIC ACID Usage And Synthesis

Chemical Properties

White to light brown crystals or powder

Uses

2-Amino-3-methoxybenzoic Acid is used in the preparation of CDK1/cyclin B inhibitors for application towards antitumor treatment. In addition, it is used in the synthesis of Alogliptin, an inhibitor o f dipeptidy peptidase, which aids in the lowering of blood-glucose for potential treatment of diabetes.

Definition

ChEBI: 3-methoxyanthranilic acid is an aminobenzoic acid that is anthranilic acid in which the hydrogen at position 3 is substituted by a methoxy group. It is a metabolite of kynurenine. It has a role as a mammalian metabolite. It is a member of benzoic acids and an aminobenzoic acid. It is functionally related to an anthranilic acid. It is a conjugate acid of a 3-methoxyanthranilate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 63, p. 6797, 1998 DOI: 10.1021/jo972158g

2-AMINO-3-METHOXYBENZOIC ACID(3177-80-8)Related Product Information

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