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2-AMINO-3-METHOXYBENZOIC ACID

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2-AMINO-3-METHOXYBENZOIC ACID Basic information

Product Name:
2-AMINO-3-METHOXYBENZOIC ACID
Synonyms:
  • 3-METHOXYANTHRANILIC ACID
  • O-ANISIDINE-6-CARBOXYLIC ACID
  • 2-AMINO-3-METHOXYBENZOIC ACID
  • 2-AMINO-M-ANISIC ACID
  • Benzoic acid, 2-amino-3-methoxy-
  • 2-AMINO-3-METHOXYBENZOIC ACID 99+%
  • 3-methoxyantharanilic acid
  • 2-azanyl-3-methoxy-benzoic acid
CAS:
3177-80-8
MF:
C8H9NO3
MW:
167.16
Product Categories:
  • Phenylacetic acid
  • Intermediates
Mol File:
3177-80-8.mol
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2-AMINO-3-METHOXYBENZOIC ACID Chemical Properties

Melting point:
169-170 °C (lit.)
Boiling point:
333.9±27.0 °C(Predicted)
Density 
1.303±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.82±0.10(Predicted)
form 
Powder
color 
White to yellow to brown
CAS DataBase Reference
3177-80-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
29225090

MSDS

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2-AMINO-3-METHOXYBENZOIC ACID Usage And Synthesis

Chemical Properties

White to light brown crystals or powder

Uses

2-Amino-3-methoxybenzoic Acid is used in the preparation of CDK1/cyclin B inhibitors for application towards antitumor treatment. In addition, it is used in the synthesis of Alogliptin, an inhibitor o f dipeptidy peptidase, which aids in the lowering of blood-glucose for potential treatment of diabetes.

Definition

ChEBI: 3-methoxyanthranilic acid is an aminobenzoic acid that is anthranilic acid in which the hydrogen at position 3 is substituted by a methoxy group. It is a metabolite of kynurenine. It has a role as a mammalian metabolite. It is a member of benzoic acids and an aminobenzoic acid. It is functionally related to an anthranilic acid. It is a conjugate acid of a 3-methoxyanthranilate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 63, p. 6797, 1998 DOI: 10.1021/jo972158g

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