BETAMETHASONE BUTYRATE PROPIONATE Chemical Properties

Melting point:

approximate 152℃

Boiling point:

613.0±55.0 °C(Predicted)

Density 

1.23±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly)

form 

Solid

pka

12.88±0.70(Predicted)

color 

White to Off-White

BETAMETHASONE BUTYRATE PROPIONATE Usage And Synthesis

Description

Betamethasone butyrate propionate (BBP) was introduced in Japan as a topical antiinflammatory agent. It is a synthetic corticosteroid with strong antiinflammatory activity at the site of inflammation but without topical or systemic side effects. On paper disk granuloma in rats, BBP was shown to have higher degree of dissociation between antiinflammation efficacy and systemic side effects than other agents in this class. Antipyretic/analgesic properties have also been reported.

Originator

Mitsubishi Kasai (Japan)

Uses

Betamethasone-17-butyrate-21-propionate are used in the treatment of vitiligo vulgaris with the combination therapy of topical steroid and vitamin D3 compound.

Definition

ChEBI: Betamethasone butyrate propionate is a corticosteroid hormone.

brand name

Antebate; Antevate

BETAMETHASONE BUTYRATE PROPIONATE(5534-02-1)Related Product Information

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