Isoflupredone Acetate
Isoflupredone Acetate Basic information
- Product Name:
- Isoflupredone Acetate
- Synonyms:
-
- 4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-pregna-(11-be
- 4-diene-3,20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregna-21-acetate
- 9-alpha-fluoroprednisoloneacetate
- 9-fluoroprednisoloneacetate
- 9-fluorprednisoloneacetate
- biorinil
- predef
- ISOFLUPREDONE ACETATE (200 MG)
- CAS:
- 338-98-7
- MF:
- C23H29FO6
- MW:
- 420.47
- EINECS:
- 206-423-9
- Product Categories:
-
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- Mol File:
- 338-98-7.mol
Isoflupredone Acetate Chemical Properties
- Melting point:
- 244-246° (dec)
- alpha
- D23 +108° (c = 0.735 in dioxane)
- Boiling point:
- 576.5±50.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly)
- form
- Solid
- pka
- 12.05±0.70(Predicted)
- color
- White to Off-White
Isoflupredone Acetate Usage And Synthesis
Uses
Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.
Definition
ChEBI: 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate is a corticosteroid hormone.
Veterinary Drugs and Treatments
Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids
can be used for its antiinflammatory or immunosuppressive
effects. Labeled indications for isoflupredone include: adjunctive
treatment of bovine ketosis, alleviating pain and lameness
associated with musculoskeletal conditions, acute hypersensitivity
reactions, adjunctive treatment of overwhelming infections with
severe toxicity, shock, supportive therapy in the treatment of stress
conditions (e.g., surgery), dystocia, retained placenta, inflammatory
ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce
inflammation associated with recurrent airway obstruction (RAO,
“heaves”, COPD).
While the drug could be used in small animals, it is recommended
to use other glucocorticoid agents instead, where there has been
more experience and other approved products for dogs and cats are
available.
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Isoflupredone Acetate(338-98-7)Related Product Information
- 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate
- Fluocinonide
- ciprocinonide
- Flumethasone 21-pivalate
- 6alpha,9-difluoro-11beta-hydroxy-16alpha,17-[isopropylidenebis(oxy)]pregna-1,4-diene-3,20-dione 21-propionate
- Isoflupredone Acetate
- Triamcinolone diacetate
- Dexamethasone-17-acetate
- Flumethasone-17-acetate
- AMCINONIDE
- Difluprednate
- Diflorasone diacetate
- Meprednisone
- Prednisone 21-acetate
- Isoflupredone
- Prednisolone
- Prednisone
- Prednisolone-21-acetate