PEG9-Tos
PEG9-Tos Basic information
- Product Name:
- PEG9-Tos
- Synonyms:
-
- Peg9-ots
- PEG9-Tos
- Tos-PEG8-OH
- 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol, 1-(4-methylbenzenesulfonate)
- OH-PEG8-Tos
- 23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricosyl 4-methylbenzenesulfonate
- HO-(CH2CH2O)8-Tos
- Tos-PEG8-OH/ 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol, 1-(4-methylbenzenesulfonate)
- CAS:
- 886469-23-4
- MF:
- C23H40O11S
- MW:
- 524.62
- Mol File:
- 886469-23-4.mol
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PEG9-Tos Chemical Properties
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
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PEG9-Tos Usage And Synthesis
Description
PEG9-Tos is a PEG linker containing a hydroxyl group with a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
PEG9-TosSupplier
Nanjing Junnahe Biopharmaceutical Co., Ltd
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- 025-58367986 17351780683
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Jinan elephant international trading co., LTD
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- 13006575422@163.com
Amatek Scientific Co. Ltd.
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- 0512-56316828
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Xi'an Confluore Biological Technology Co., Ltd.
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Angel Pharmatech, Ltd.
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- 17317130613
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