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Tenapanor HCl

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Tenapanor HCl Basic information

Product Name:
Tenapanor HCl
Synonyms:
  • Tenapanor HCl
  • Tenapanor dihydrochloride
  • Tenapanor hydrochloride
  • AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; TENAPANOR; TENAPANOR HYDROCHLORIDE; TENAPANOR DIHYDROCHLORIDE; IBSRELA.
  • 17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide dihydrochloride
  • AZD1722 hydrochloride
  • RDX5791 hydrochloride
  • Tenapanor 2HCl
CAS:
1234365-97-9
MF:
C50H68Cl6N8O10S2
MW:
1217.97052
EINECS:
810-634-7
Mol File:
1234365-97-9.mol
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Tenapanor HCl Chemical Properties

storage temp. 
-20°C
solubility 
DMSO: soluble
form 
A crystalline solid
color 
White to off-white
Water Solubility 
Water: soluble
InChIKey
VFRAXTZDILCRKY-OWRGXFNZSA-N
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Tenapanor HCl Usage And Synthesis

Uses

Tenapanor (AZD1722) HCl is a potent, orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor HCl reduces intestinal phosphate absorption predominantly through the reduction of passive paracellular phosphate flux. Tenapanor HCl has the potential to be used in research on hyperphosphatemia.

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