4,4'-DI-TERT-BUTYLBIPHENYL Chemical Properties

Melting point:

126-130 °C(lit.)

Boiling point:

190-192 °C13 mm Hg(lit.)

Density 

0.9463 (estimate)

refractive index 

1.5928 (estimate)

Flash point:

190-192°C/13mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

dioxane: 0.1 g/mL, clear

form 

Crystalline Powder

color 

Light yellow to yellow-orange

BRN 

2095855

CAS DataBase Reference

1625-91-8(CAS DataBase Reference)

NIST Chemistry Reference

4,4'-Di-tert-butylbiphenyl(1625-91-8)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

29029090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4,4'-DI-TERT-BUTYLBIPHENYL Usage And Synthesis

Chemical Properties

Powder

Uses

It is used in the generation of 1,2-di(lithiomethyl)benzene. It is found to accept electrons from Li metal to give a radical anion which is highly effective in the conversion of alkyl halides to alkyllithiums. 4,4?-Di-tert-butylbiphenyl is used in production of homoallylic amine derivatives. It is also used in the preparation of lithium di-tert-butylbiphenylide, a radical anion, superior to sodium or lithium naphthalenides for metalation reactions. Along with lithium, 4,4?-Di-tert-butylbiphenyl catalyzes; reaction of chloromethyl ethyl ether and different carbonyl compounds to yield corresponding hydroxyethers and reductive opening of N-phenylazetidine.

Synthesis Reference(s)

Tetrahedron Letters, 26, p. 1655, 1985 DOI: 10.1016/S0040-4039(00)98576-9

General Description

4,4′-Di-tert-butylbiphenyl along with lithium catalyzes:

• reaction of chloromethyl ethyl ether and different carbonyl compounds to yield corresponding hydroxyethers
• reductive opening of N-phenylazetidine

4,4'-DI-TERT-BUTYLBIPHENYL(1625-91-8)Related Product Information

• 3,5-Bis(tert-butyl)benzaldehyde
• 1,3-DI-TERT-BUTYLBENZENE
• 3,5-Di-tert-butyl-4-hydroxybenzyl alcohol
• Bis(4-tert-butylphenyl)iodonium hexafluorophosphate
• Ultranox 626
• 4,4'-[[2,5-Bis(tert-butyl)-1,4-phenylene]bis(oxy)]bis[3-(trifluoromethyl)benzenamine
• 2,7-Di-tert-butylfluorene
• 4,4'-DI-TERT-BUTYLBIPHENYL
• 1,4-Di-tert-butylbenzene
• 2,6-Di-tert-butyl-p-benzoquinone
• 4-Bromo-2,6-di-tert-butylanisole
• Antioxidant 168
• 2,4-Di-tert-butylphenyl 3,5-di-tert-butyl-4-hydroxybenzoate
• 4,4'-Methylenebis(2,6-di-tert-butylphenol)
• 3,5-Di-tert-butylcatechol
• 2 7-DI-TERT-BUTYL-9-FLUORENYLMETHANOL
• Pseudomorphine (Morphine Impurity)
• CODEINE IMP C