DEA Chemical Properties

Boiling point:

544.5±50.0 °C(Predicted)

Density 

0.932±0.06 g/cm3(Predicted)

storage temp. 

Desiccate at -20°C

solubility 

DMF: 10 mg/ml; DMSO: 30 mg/ml; Ethanol: 100 mg/ml; Ethanol:PBS (1:2): 8 mg/ml; PBS (pH 7.2): <100 μg/ml

pka

14.49±0.10(Predicted)

DEA Usage And Synthesis

Description

Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB₁ receptors with potency and efficacy similar to that of AEA. However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.

Uses

(7Z,10Z,13Z,16Z)-N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide is an endocannabinoid and an analog of anandamide, which is an endogenous cannabinoid and TRPV1 receptor agonist.

Definition

ChEBI: 7,10,13,16-Docosatetraenoylethanolamine is a N-acylethanolamine 22:4.

Biological Activity

Potent endocannabinoid ( anandamide analog) that activates CB 1 receptors in microglia and binds to rat synaptosomal membranes (K I = 34.4 nM). Cannabimimetic in vivo .

DEA(150314-35-5)Related Product Information

• ANANDAMIDE,Anandamide(inTocrisolveTM100),anandamide(20.4,n-6
• ANANDAMIDE
• ANANDAMIDE PHOSPHATE
• ANANDAMIDE, [ARACHIDONYL-1-14C]
• ANANDAMIDE [ETHANOLAMINE 1,2-14C]
• ANANDAMIDE
• DEA
• ARACHIDONYL TRIFLUOROMETHYL KETONE INHIB ITS ANANDAMIDE H
• ANANDAMIDE-D8
• ANANDAMIDE, 2'-FLUORO,2'-FLUORO ANANDAMIDE
• ANANDAMIDE, [ETHANOLAMINE 1-3H]
• [3H]-Anandamide,ANANDAMIDE [ARACHIDONYL-5,6,8,9,11,12,14,15-3H]
• ANANDAMIDE (IN WATER SOLUBLE EMULSION)
• anandamide hydroxylase
• anandamide amidohydrolase
• conjugated triene anandamide
• ANTI-ANANDAMIDE AMIDOHYDROLASE
• ANANDAMIDE (PURE OIL)