Basic information Safety Supplier Related

(S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDE

Basic information Safety Supplier Related

(S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDE Basic information

Product Name:
(S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDE
Synonyms:
  • (S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDE
  • (S)-WAY 100135 DIHYDROCHLORIDE
  • (S)-WAY1001352HCl
  • WAY 100135
  • N-(1,1-Dimethylethyl)-4-(2-methoxyphenyl)-alpha-phenyl-1-piperazinepropanamide
  • WAY 100478
  • 1-Piperazinepropanamide, N-(1,1-dimethylethyl)-4-(2-methoxyphenyl)-α-phenyl-
CAS:
133025-23-7
MF:
C24H33N3O2
MW:
395.54
Mol File:
133025-23-7.mol
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(S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDE Chemical Properties

Melting point:
>183°C (dec.)
Boiling point:
582.8±50.0 °C(Predicted)
Density 
1.085
storage temp. 
Desiccate at +4°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
15.63±0.46(Predicted)
color 
White
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(S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDE Usage And Synthesis

Uses

(S)-WAY 100135 Dihydrochloride is a selective 5-?HT1A receptor antagonist.

Definition

ChEBI: N-tert-butyl-3-[4-(2-methoxyphenyl)-1-piperazinyl]-2-phenylpropanamide is a member of piperazines.

Biological Activity

Potent, selective 5-HT 1A receptor antagonist (IC 50 = 15 nM). Selective over 5-HT 1B , 1C , 2 , α 1 , α 2 and D 2 receptors (IC 50 > 1000 nM). Centrally active on systemic administration.

(S)-N-TERT-BUTYL-3-(4-(2-METHOXYPHENYL)-PIPERAZIN-1-YL)-2-PHENYLPROPANAMIDE DIHYDROCHLORIDESupplier

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